What is Diaper Rash? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

Diaper Rash overview

BRAND NAMES:

  • Augmentin, Augmentin ES-600, Augmentin XR, Aquaphor Healing Cream Baby, Aquaphor Healing Paste Baby, Balmex Adultcare, Balmex Diaper Rash, Boudreaux's Butt Paste, Cozima, Desitin Daily Defense Creamy, Desitin Maximum Strength Original, Desitin Original, Diaper Rash, Dr. Smith's Adult Barrier, Dr. Smith's Diaper, Good Neighbor Pharmacy Diaper Rash Creamy, Good Neighbor Pharmacy Zinc Oxide, Good Sense Diaper Rash

Generic Names:

  • Diaper Rash

Uses:

  • Treats and prevents diaper rash., Treats infections. This medicine is a penicillin antibiotic.

Therapeutic Classes:

  • Antibiotic, Protectant, Dermatological

Forms:

  • Cream, Ointment, Paste, Liquid, Tablet, Chewable Tablet, Long Acting Tablet

How it’s taken:

  • By mouth, On the skin

What is Diaper Rash used for?

What form(s) does Diaper Rash come in?

  • Cream

  • Ointment

  • Paste

  • Liquid

  • Tablet

  • Chewable Tablet

  • Long Acting Tablet

What are common Diaper Rash dosages?

  • Tube 56GM of 40%

How to take Diaper Rash

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take this medicine with a snack or at the beginning of a meal to help prevent nausea.

  • Chewable tablets: Chew the tablet completely before you swallow it.

  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Shake the medicine well just before you measure each dose. Rinse the spoon or dropper after each use.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Tablet, extended-release tablet, chewable tablet: Store at room temperature, away from heat, moisture, and direct light.

  • Oral liquid: Store in the refrigerator. Do not freeze.

  • Throw away any unused oral liquid after 10 days.

  • Swallow the extended-release tablet whole. Do not crush, break, or chew it.

  • Tablet, extended-release tablet, chewable tablet: Store at room temperature, away from heat, moisture, and direct light.

  • Take this medicine with a snack or at the beginning of a meal to help prevent nausea.

  • Oral liquid: Store in the refrigerator. Do not freeze.

  • Chewable tablets: Chew the tablet completely before you swallow it.

  • Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

  • Throw away any unused oral liquid after 10 days.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup. Shake the medicine well just before you measure each dose. Rinse the spoon or dropper after each use.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

  • Topical application routeWash your hands with soap and water before and after you use this medicine.

  • Clean the baby's diaper area with mild soap and water. Allow the skin to dry before you apply the medicine and put on a new diaper.

  • Apply the medicine to the diaper area every time you change the diaper. Use this medicine any time the baby might be in a wet diaper for a longer time, such as at nap time or overnight.

  • Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.

  • Apply the medicine to the diaper area every time you change the diaper. Use this medicine any time the baby might be in a wet diaper for a longer time, such as at nap time or overnight.

  • Topical application routeWash your hands with soap and water before and after you use this medicine.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Clean the baby's diaper area with mild soap and water. Allow the skin to dry before you apply the medicine and put on a new diaper.

  • Follow the instructions on the medicine label if you are using this medicine without a prescription.

What to do if you miss a dose of Diaper Rash

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Topical application routeAsk your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Diaper Rash contraindications - Who shouldn't take Diaper Rash?

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to amoxicillin, clavulanate, or a similar antibiotic (penicillin or cephalosporin), or if you had liver problems caused by Augmentin®.

  • Do not use this medicine if your child has had an allergic reaction to zinc oxide. Do not use on deep or puncture wounds, cuts, or infections.

Diaper Rash warnings

  • Call your doctor if the diaper rash gets better and then comes back.

  • Call a poison control center right away if anyone accidentally swallows the medicine.

  • If the diaper rash symptoms do not improve within 7 days or if they get worse, call your doctor.

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or mononucleosis (mono).

  • Birth control pills may not work as well while you are taking this medicine. Use another form of birth control to prevent pregnancy.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • The chewable tablet and oral liquid contain phenylalanine. Talk to your doctor before you use this medicine if you have phenylketonuria (PKU).

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Diaper Rash interactions & what to avoid when taking Diaper Rash

  • Some medicines can affect how this medicine works. Tell your doctor if you are taking a blood thinner (such as warfarin), allopurinol, or probenecid.

  • Birth control pills may not work as well while you are taking this medicine. Use another form of birth control to prevent pregnancy.

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • The chewable tablet and oral liquid contain phenylalanine. Talk to your doctor before you use this medicine if you have phenylketonuria (PKU).

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Check with your doctor to find out if you can use other skin care products on the treated skin areas.

  • Call your doctor if the diaper rash gets better and then comes back.

  • Call a poison control center right away if anyone accidentally swallows the medicine.

Diaper Rash side effects - How does Diaper Rash make you feel?

Serious Side Effects

  • Blistering, peeling, red skin rash

  • Change in how much or how often you urinate

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow eyes or skin

  • Diarrhea that may contain blood, stomach cramps

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Mild diarrhea, nausea, vomiting

  • Tooth discoloration (in children)

  • Diaper rash