What is Droperidol? Uses, warnings & side effects

Updated May 14, 2025  •  Published Apr 11, 2021

Droperidol overview

BRAND NAMES:

Generic Names:

  • Droperidol

Uses:

  • Prevents nausea and vomiting that may occur after surgery or diagnostic procedures.

Therapeutic Classes:

  • Anesthetic Adjunct, Antiemetic

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Droperidol used for?

What form(s) does Droperidol come in?

  • Injectable

What are common Droperidol dosages?

  • Vial 2ML of 2.5MG/ML

Droperidol images - What does Droperidol look like?

  • droPERidol
    2ml of 2.5mg/ml vial

How to take Droperidol

  • Your doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein or as a shot into a muscle.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Droperidol

Droperidol contraindications - Who shouldn't take Droperidol?

  • This medicine is not right for everyone. You should not receive this medicine if you had an allergic reaction to droperidol, or if you have a heart rhythm problem (a QT interval problem).

Droperidol warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart disease, congestive heart failure, a slow heartbeat, pheochromocytoma, or low magnesium or potassium levels in the blood.

  • This medicine may cause the following problems:Heart rhythm problems (QT prolongation)Low blood pressureNeuroleptic malignant syndrome (NMS), very rarely

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Your doctor will check your progress after you receive this medicine to see if the medicine is working properly and to check for unwanted effects.

  • Lightheadedness, dizziness, or fainting

Droperidol interactions & what to avoid when taking Droperidol

  • Some foods and medicines can affect how this medicine works. Tell your doctor if you are using any of the following:An MAO inhibitorDiuretic (water pill)Medicine for heart rhythm problemsBlood pressure medicineMedicine for depression or mental illness

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Your doctor will check your progress after you receive this medicine to see if the medicine is working properly and to check for unwanted effects.

Droperidol side effects - How does Droperidol make you feel?

Serious Side Effects

  • Fever, sweating, confusion, uneven heartbeat, muscle stiffness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Chest pain

  • Lightheadedness, dizziness, or fainting

  • Fast, pounding, or uneven heartbeat

Less Serious Side Effects

  • Feeling drowsy, restless, anxious, or hyperactive