Effexor XR Coupons & Prices

Effexor XR is an FDA-approved, brand-name, prescription drug that is used in the treatment of depression, anxiety, panic attacks, and social anxiety disorder. It is an extended-release capsule that is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant. The generic version of Effexor XR is venlafaxine ER. Effexor XR has an average cash price of $778.61 for 30, 150mg capsules extended release 24 hour; however, you could fill your Rx for $6.46 for 30, 150mg capsules extended release 24 hour of generic Effexor XR using a free SingleCare prescription discount card. You can save when you use our SingleCare Effexor XR coupon at participating pharmacies.

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7 capsule extended release 24 hour37.5mgEdit

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Effexor XR coupon at Kroger Pharmacy
$9.46
$ 6.46
$3 off with signupwith signup

Show this free card to your pharmacist.

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Effexor XR coupon at Harris Teeter Pharmacy
$9.46
$ 6.46
$3 off with signupwith signup

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Effexor XR coupon at Walmart Neighborhood Market Pharmacy
$ 15.00
Effexor XR coupon at Walmart Pharmacy
$ 15.00
Effexor XR coupon at Food Lion Pharmacy
$ 16.47
Effexor XR coupon at Walgreens Pharmacy
$20.16
$ 17.16
$3 off with signupwith signup
$ 17.24
$ 20.99
$25.74
$ 22.74
$3 off with signupwith signup

About SingleCare Pricing

SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.

Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.

Prices updated: 12/05/2025

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About Effexor XR

Effexor XR is an FDA-approved, brand-name, prescription drug that is used in the treatment of depression, anxiety, panic attacks, and social anxiety disorder. It is an extended-release capsule that is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant. The generic version of Effexor XR is venlafaxine ER. Effexor XR has an average cash price of $778.61 for 30, 150mg capsules extended release 24 hour; however, you could fill your Rx for $6.46 for 30, 150mg capsules extended release 24 hour of generic Effexor XR using a free SingleCare prescription discount card. You can save when you use our SingleCare Effexor XR coupon at participating pharmacies.

Effexor XR Price History & Information

Price History for Effexor Xr (Brand) & Venlafaxine Hcl Er (Generic)

30 count, capsule extended release 24 hour, 150mg

Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.

Average 1-Month Prices for Effexor Xr (Brand) & Venlafaxine Hcl Er (Generic)

30 count, capsule extended release 24 hour, 150mg
PharmacyEffexor Xr Retail PriceVenlafaxine Hcl Er Retail PriceVenlafaxine Hcl Er SingleCare Price
CVS Pharmacy-$118.43$40.45
Walmart-$22.47$15.00
Walgreens$783.50$132.80$53.62
Kroger Pharmacy$801.00$59.40$7.36
Albertsons Pharmacy-$54.60$20.76

These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.

About Effexor XR

Effexor XR is an FDA-approved, brand-name, prescription drug that is used in the treatment of depression, anxiety, panic attacks, and social anxiety disorder. It is an extended-release capsule that is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant. The generic version of Effexor XR is venlafaxine ER. Effexor XR has an average cash price of $778.61 for 30, 150mg capsules extended release 24 hour; however, you could fill your Rx for $6.46 for 30, 150mg capsules extended release 24 hour of generic Effexor XR using a free SingleCare prescription discount card. You can save when you use our SingleCare Effexor XR coupon at participating pharmacies.

Effexor XR FAQs

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

How much does Effexor XR cost without insurance?

Without insurance coverage, the retail price of Effexor XR could typically be around $778.61 for 30, 150mg capsules extended release 24 hour. Many customers could pay a discount price of $6.46 for 30, 150mg capsules extended release 24 hour of generic Effexor XR with a SingleCare coupon. Local pharmacies that accept a SingleCare prescription savings card include CVS Pharmacy, Walmart, Kroger, Fry's, and more.

How much does Effexor XR cost with insurance?

The average copay for Effexor XR may vary depending on your type of insurance plan and level of coverage. You could pay a discounted price of $6.46 for 30, 150mg capsules extended release 24 hour of generic Effexor XR with your free and easy-to-use SingleCare discount card at your neighborhood drugstore. Ask your pharmacist to compare prices between your insurance copay and SingleCare discount to ensure that you are getting the lowest price possible for your Effexor XR prescription. Repeat this for all of your prescription medications to get maximum savings.

Does Medicare cover Effexor XR and how much does it cost?

Brand-name Effexor XR is not covered by Medicare prescription plans, but they generally pay for the generic. Also, you can pay a reduced price of $6.46 for 30, 150mg capsules extended release 24 hour of generic Effexor XR by choosing generic and using a SingleCare discount card at your local drugstore.

Is there a generic of Effexor XR?

Effexor XR is the brand-name version while venlafaxine ER is the generic version.

What is Effexor XR?

Effexor XR is a branded prescription drug that is approved by the FDA to treat major depressive disorder, anxiety, panic disorder, and social anxiety disorder. Effexor XR is an extended-release capsule that is classified as a serotonin-norepinephrine reuptake inhibitor (SNRI) antidepressant. Effexor XR restores the balance of serotonin and norepinephrine in the brain to decrease fear, anxiety, and the risk of panic attacks.

Ask your doctor before using Effexor XR if you are pregnant, planning to become pregnant, or breastfeeding.

You should consult with your doctor before starting treatment using Effexor XR. Prescribing information given by your doctor should be followed closely.

Effexor XR is meant to be taken once daily and recommended to be taken with food. Do not chew, crush, or open Effexor XR. It may take several weeks for symptoms to begin to improve, do not increase or decrease dosages or frequency unless your doctor tells you to do so. Do not stop taking Effexor XR suddenly, as doing so can cause side effects. Monitor blood pressure regularly while taking Effexor XR. Avoid alcohol while taking Effexor XR. Do not drive until you know how the medicine affects you. 

What are the side effects of Effexor XR?

Some but not all of the common side effects include dry mouth, nausea, blurred vision, trouble sleeping, headache, dizziness, appetite loss, sleepiness, and sexual problems. Severe allergic reactions to Effexor XR are not common. However, immediately get emergency medical help if you have symptoms of an allergic reaction like hives, difficulty breathing, or swelling of the face, lips, throat, or tongue. 

It is important to note that stopping or lowering the medication may cause some common side effects. Closely monitor your mental condition and immediately seek medical attention should you experience increased depression or suicidal thoughts.

This is not a complete list of side effects. Consult your doctor or healthcare professional for additional information and medical advice regarding other possible side effects or drug interactions.

Medically reviewed by Karen BergerPharm.D.
Licensed Pharmacist

After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.

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Where are Effexor XR coupons from SingleCare accepted?

SingleCare is accepted at most national pharmacies and grocers, including the following:

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