What is L-Methylfolate Calcium: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

L-Methylfolate Calcium overview

BRAND NAMES:

  • Beyaz, Rajani, Safyral, Tydemy

Generic Names:

  • L-Methylfolate Calcium

Uses:

  • Used as a dietary supplement for depression and schizophrenia. This is a medical food.

Therapeutic Classes:

  • Contraceptive Combination, Nutriceutical, Nutritive Agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is L-Methylfolate Calcium used for?

What form(s) does L-Methylfolate Calcium come in

  • Tablet

What are common L-Methylfolate Calcium doses?

  • Tablet 7.5MG

  • Tablet 15MG

Common L-Methylfolate Calcium prescriptions

  • L-methylfolate Calcium
    15mg tablet

  • L-methylfolate Calcium
    7.5mg tablet

How to take L-Methylfolate Calcium

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

What to do if you miss a dose of L-Methylfolate Calcium

  • Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

L-Methylfolate Calcium contraindications

  • Do not use this medicine if you have had an allergic reaction to L-methylfolate.

L-Methylfolate Calcium warnings

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Make sure your doctor knows if you are pregnant or breastfeeding, or if you have anemia, vitamin B12 deficiency, or a history of bipolar disorder.

L-Methylfolate Calcium interactions

  • Make sure your doctor knows if you also use aminopterin, capecitabine (Xeloda®), fluoxetine (Prozac®), isotretinoin (Accutane®), metformin (Glucophage®), methotrexate (Trexall®), methylprednisolone (Medrol®), pentamidine (Nebupent®), pyrimethamine (Daraprim®), triamterene (Dyrenium®), trimethoprim (Bactrim®, Septra®), medicine to treat seizures (such as carbamazepine, lamotrigine, phenobarbital, phenytoin, primidone, valproic acid, Depakene®, Dilantin®, Tegretol®), an NSAID pain or arthritis medicine (such as aspirin, diclofenac, ibuprofen, indomethacin, naproxen, sulindac, Advil®, Aleve®, Celebrex®, Voltaren®), a blood thinner (such as warfarin, Coumadin®, Jantoven®), or birth control pills.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

L-Methylfolate Calcium side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

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