What is Methocarbamol: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Methocarbamol is a generic muscle relaxant used to relieve pain and discomfort due to muscle or bone problems such as sprains or muscle injury. It is an older drug, so it isn’t always a first choice. As with other muscle relaxants, methocarbamol does have risks, but health professionals haven’t thoroughly studied these risks and determined their likelihood.

Methocarbamol overview

BRAND NAMES:

  • Robaxin

Generic Names:

  • Methocarbamol

Uses:

  • Treats muscle pain and spasms

Therapeutic Classes:

  • Centrally-acting muscle relaxant, anti-spasmodic agent

Forms:

  • Tablet, injection

How it’s taken:

  • By mouth or intravenous/intramuscular injection

What is Methocarbamol used for?

Methocarbamol relieves pain due to muscle spasms, muscle injuries, and bone problems such as sprains. Methocarbamol is also FDA-approved to relieve muscle rigidity due to tetanus, but it’s usually not a first choice.

What form(s) does Methocarbamol come in

  • Tablet

    • 500 mg

    • 750 mg

  • Injection

    •  100 mg/mL

What are common Methocarbamol doses?

  • For muscle pain and muscle spasms in adults: 1,500 mg by mouth every 6 hours for 2–3 days and then 1,000 mg by mouth every 6 hours

  • For tetanus in adults: 1,000–3,000 mg IV given once and then 1,000–2,000 mg IV, oral dose, or through a nasogastric tube

    • In children: 15 mg/kg IV or tablets given every six hours for 2–3 days

RELATED: Methocarbamol dosage, forms, and strengths

Common Methocarbamol prescriptions

  • Methocarbamol
    1000mg tablet

  • Methocarbamol
    500mg tablet

  • Methocarbamol
    750mg tablet

  • Methocarbamol
    10ml of 1000mg/10ml vial

How to take Methocarbamol

  • Take your medicine as directed. Your dose may need to be changed over the course of treatment.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Methocarbamol

  • Take the missed dose as soon as you remember within one hour of its scheduled time. If more than an hour has passed, skip the missed dose and take the next dose at its scheduled time.

  • You should not use two doses at the same time.

Methocarbamol contraindications

  • This medicine is not right for everyone. 

  • Do not use it if you have had an allergic reaction to methocarbamol.

Methocarbamol warnings

  • Tell any doctor or other healthcare provider who treats you that you are using this medicine. Methocarbamol may affect the results of some medical tests.

  • Your doctor may need to check your progress and monitor for side effects. Keep all appointments. 

  • Before taking this medicine, tell your doctor if you are pregnant or breastfeeding or if you have:

    • Kidney disease

    • Liver disease

    • A history of seizures

    • A muscle weakness disorder called myasthenia gravis.

  • This medicine may make you dizzy or drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

  • Keep this medicine out of the reach of children.

Methocarbamol interactions

  • To avoid potentially hazardous drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medicines, and supplements you are using before taking diazepam.

  • Tell other healthcare providers you are using this medicine before they prescribe new medications.

  • Tell your doctor if you’re taking pyridostigmine, a drug used to treat myasthenia gravis. Methocarbamol can reduce its effectiveness in treating that disorder.

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, sedatives, antidepressants, anxiety medications, and alcohol.

  • Avoid drinking alcohol while you are using this medicine.

Methocarbamol side effects

Serious side effects

Talk to a doctor if you notice any signs or symptoms of a possible serious side effect including:

  • Seizures

  • Blurred vision, redness, pain, or swelling of the eyes

  • Slow heartbeat

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Lightheadedness, dizziness, fainting

  • Infections

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less serious side effects

  • Dizziness

  • Drowsiness

  • Stomach upset

  • Metallic taste

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.