Sirolimus is a generic prescription drug that, in combination with cyclosporine and a steroid medication, suppresses the immune system to prevent organ rejection after a kidney transplant in patients 13 years of age or older. Sirolimus blocks chemicals that activate white blood cells to mount an immune system attack on a transplanted organ. Organ rejection is what happens when the immune system attacks the transplanted organ or tissue. The retail price Sirolimus is $492.02 for 30, 1mg tablets, but it can be reduced to $35.58 for 30, 1mg tablets.
Edit your dosage
9 solution (quantity in ml), 1mg/mlEdit
Unlock members-only prices.Free signup.
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.

Save an extra $3 on any eligible prescription! Sign up for free
Members can save even more
and it's free to join
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
Sirolimus is a generic prescription drug that, in combination with cyclosporine and a steroid medication, suppresses the immune system to prevent organ rejection after a kidney transplant in patients 13 years of age or older. Sirolimus blocks chemicals that activate white blood cells to mount an immune system attack on a transplanted organ. Organ rejection is what happens when the immune system attacks the transplanted organ or tissue. The retail price Sirolimus is $492.02 for 30, 1mg tablets, but it can be reduced to $35.58 for 30, 1mg tablets.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Sirolimus Retail Price | Sirolimus SingleCare Price |
|---|---|---|
| CVS Pharmacy | $486.90 | $31.95 |
| Walgreens | $252.30 | $165.90 |
| Kroger Pharmacy | $509.52 | $127.26 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Sirolimus is a generic prescription drug that, in combination with cyclosporine and a steroid medication, suppresses the immune system to prevent organ rejection after a kidney transplant in patients 13 years of age or older. Sirolimus blocks chemicals that activate white blood cells to mount an immune system attack on a transplanted organ. Organ rejection is what happens when the immune system attacks the transplanted organ or tissue. The retail price Sirolimus is $492.02 for 30, 1mg tablets, but it can be reduced to $35.58 for 30, 1mg tablets.
At most pharmacies, the full cash price of Sirolimus will be $492.02 for 30, 1mg tablets. That same prescription will cost $35.58 for 30, 1mg tablets using a SingleCare savings card, which you can use at participating pharmacies such as CVS pharmacy, Walmart, Kroger, and Walgreens.
Depending on your insurance plan, the copay pricing of Sirolimus will vary. With a SingleCare Sirolimus coupon, though, Sirolimus costs $35.58 for 30, 1mg tablets, which may be lower than your copay. To get the best price on Sirolimus, compare your insurance copay to SingleCare’s discount.
If you have Medicare, Sirolimus should be covered, either under your Medicare prescription drug plan or by Medicare Part B. If you don't have Medicare coverage, consider using a SingleCare Sirolimus coupon for your prescription. With SingleCare, the price of Sirolimus is $35.58 for 30, 1mg tablets.
Sirolimus is a generic drug manufactured by Zydus, Amneal, Teva, and other generic manufacturers. The brand name version is called Rapamune.
Sirolimus is a generic prescription drug that, in combination with cyclosporine and a steroid, suppresses the immune system to prevent organ rejection after a kidney transplant. Organ rejection is a process in which the body responds to a transplanted organ as if it were an infection. White blood cells are activated, chemicals are released, and the body begins to damage and destroy the cells in the transplanted organ. Sirolimus “slows down” the immune system by blocking chemicals in the body that activate white blood cells.
Sirolimus is first administered right after transplant surgery and is meant to be taken with cyclosporine, another immune-suppressing drug, as well as a steroid medication. Sirolimus has a boxed warning, which is the most serious warning required by the FDA (US Food and Drug Administration). Sirolimus can cause increased risk of infection as well as lymphoma and other malignancies. Sirolimus should only be prescribed by a physician who is experienced with immunosuppressant medications and kidney transplant patients. Sirolimus should not be used in lung or liver transplant patients.
Talk to your doctor or healthcare professional about what side effects to expect with Sirolimus. Tell your doctor about all of the medical conditions you have, and any medications you take, including prescription, over-the-counter, and vitamins or supplements. Consult your doctor or healthcare professional for additional information and medical advice.
After receiving her doctorate from the University of Pittsburgh School of Pharmacy, Karen Berger, Pharm.D., has worked in both chain and independent community pharmacies. She currently works at an independent pharmacy in New Jersey. Dr. Berger enjoys helping patients understand medical conditions and medications—both in person as a pharmacist, and online as a medical writer and reviewer.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved