List of lipase inhibitors: Uses, common brands, and safety information

Key takeaways

• Lipase inhibitors like orlistat help with weight loss by blocking the digestion and absorption of fat from food.

• Orlistat, the only FDA-approved lipase inhibitor, comes as prescription Xenical and over-the-counter (OTC) Alli to support weight management.

• These medications work best when combined with a balanced diet and exercise, helping people lose weight and maintain it long-term.

• Common side effects include oily stools, gas with discharge, and increased bowel movements.