The standard Colace dosage for occasional constipation in adults is one to three capsules daily in one or divided doses.
The max dose of Colace for adults is 300 mg daily.
Colace is available as capsules.
The best time to take Colace is as needed in single or divided doses daily.
Do not take Colace if you experience rectal bleeding or if constipation does not improve after taking Colace for seven days.
Colace is an over-the-counter (OTC) stool softener used to treat occasional constipation in adults and children 2 years and older. Its active ingredient is docusate sodium, a gentle laxative that works by pulling water and fat into the stool to soften it and allow for a more comfortable bowel movement. Colace is taken as a capsule once or twice daily.
Colace is a brand name for a family of laxatives. Colace capsules and softgels contain docusate sodium and are available in regular strength (100 mg) and extra strength (250 mg) formulations. Colace Clear comes as low-dose softgels (50 mg). Other Colace products contain different active ingredients and are available as tablets or gummies.
Capsules, softgels: 50, 100 mg, 250 mg
Colace dosage chart |
|||
|---|---|---|---|
| Indication | Starting dosage | Standard dosage | Maximum dosage |
| Constipation (regular strength) | 50–300 mg daily in a single dose or divided doses | 50–300 mg daily in a single dose or divided doses | 300 mg daily |
| Constipation (extra strength) | 250 mg taken once daily | 250 mg taken once daily | 250 mg daily |
Colace dosage chart for children |
|
|---|---|
| Age | Recommended dosage (tablet) |
| 2-11 years | 100 mg daily (regular strength) or 150 mg daily (Colace Clear) |
| 12 years and older | 50–300 mg daily (regular strength) or 250 mg daily (extra strength) |
Colace requires no dosage adjustments for liver problems, kidney problems, or other medical conditions.
Children younger than 12 should only take one regular-strength Colace capsule daily (or three Colace Clear capsules). Don’t give young children extra-strength Colace capsules without consulting a healthcare professional.
Colace is a gentle drug. Side effects are mild and rare, typically limited to diarrhea, stomach pain, cramping
, or throat irritation.
However, Colace should not be taken by anyone who has had an allergic reaction to it or who is using mineral oil. It should also be avoided in people with severe abdominal pain, swelling, or fever, as these could be signs of an intestinal obstruction or infection.
Get medical advice before taking Colace if you have noticed a sudden change in bowel habits or are experiencing abdominal pain, nausea, or vomiting.
Stop using Colace and talk to a healthcare provider if:
You experience rectal bleeding
You don’t have a bowel movement after taking Colace
Constipation persists after taking Colace for seven days.
Keep Colace out of the reach of children.
Colace is taken by mouth, with or without food. This medication is usually taken once or twice daily in equal doses.
Read the instructions on the package. Each Colace product has slightly different dosages and directions.
Swallow the capsule or softgel whole with a full glass of water.
Store Colace at room temperature.
You should have a bowel movement 12 to 72 hours after taking a Colace dose. Call a healthcare professional if you don’t.
Docusate sodium works entirely in the intestines, with only a minimal amount absorbed into the blood. About 12 to 72 hours
after taking a dose, almost the entire Colace dose is excreted in the stools.
Take a missed Colace dose as soon as you remember. If it’s almost time for your next dose, skip the missed dose and continue your normal schedule. Do not exceed the maximum daily dosage.
Do not take Colace for longer than one week without consulting a healthcare provider. In some cases, a healthcare provider may prescribe Colace for long-term treatment of constipation associated with other drugs or conditions.
Colace can be stopped at any time without problems. If constipation returns when Colace is stopped, talk to a healthcare provider.
Adults should not take more than 300 mg of Colace in a 24-hour period, and children between the ages of 2 and 11 should not take more than 150 mg per day.
Taking too much Colace may result in dehydration or an electrolyte imbalance. Call a poison control center or get emergency medical help if too much Colace is taken.
Colace has very few drug interactions. The most significant is mineral oil, which should never be taken with Colace except under the direction of a healthcare provider.
Colace may cause problems if taken with other laxatives or prescription drugs that cause low potassium.
RELATED: Colace vs. Dulcolax
There is no evidence that Colace interacts with alcohol. However, alcohol dehydrates the body just as Colace does. Use alcohol cautiously when taking any kind of laxative.
Colace is believed to be safe to take while pregnant or lactating. It’s minimally absorbed into the body and not present in breast milk. However, pregnant or nursing women should consult a healthcare provider before taking Colace.
Colace is not FDA-approved for pets, but a vet may prescribe docusate for constipation or problems with hard feces. Colace comes in fixed-dose capsules, so the vet may prescribe another dosage form to allow for smaller doses. Cats may be given docusate enemas or suppositories.
The standard veterinary docusate dosage for dogs and cats is 2 mg per kg of body weight per day.
Colace, Atlantis Consumer Healthcare
Colace docusate sodium capsule drug information, DailyMed (NIH National Library of Medicine)
Colace drug summary, Prescriber’s Digital Reference (PDR)
Colace Extra Strength Stool Softener docusate sodium capsule drug information, DailyMed (NIH National Library of Medicine)
Docusate, PubChem
Docusate, StatPearls
Docusate solution, suspension, or syrup, Cleveland Clinic
Cathartic and laxative drugs, Merck Veterinary Manual
Anne Jacobson, MD, MPH, is a board-certified family physician, writer, editor, teacher, and consultant. She is a graduate of University of Wisconsin School of Medicine and Public Health, and trained at West Suburban Family Medicine in Oak Park, Illinois. She later completed a fellowship in community medicine at PCC Community Wellness and a master's in Public Health at the University of Illinois-Chicago. She lives with her family near Chicago.
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