What is Premphase: Uses, Warnings & Interactions

How to take Premphase

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• Take this medicine at the same time each day.

• Your doctor may want you to take calcium or vitamin D supplements while you take this medicine.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

• Take this medicine at the same time each day.

• Your doctor may want you to take calcium or vitamin D supplements while you take this medicine.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Premphase

Premphase contraindications

• This medicine is not right for everyone. Do not use it if you had a severe allergic reaction to estrogens, you have liver disease, cancer of the breast, uterus, or ovaries, or a history of blood clotting problems, heart attack, or stroke. Do not use it if you may be pregnant, are breastfeeding, or have unusual vaginal bleeding that has not been checked by a doctor.

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to estrogen or progestin, or you are pregnant or have unusual vaginal bleeding not checked by a doctor. Do not use this medicine if you have a history of liver disease, breast cancer, blood clots or clotting problems, heart attack, or stroke, or you had a hysterectomy.

Premphase warnings

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

• Tell your doctor if you are breastfeeding or if you have endometriosis, asthma, diabetes, epilepsy, heart failure, high blood pressure, high cholesterol, kidney disease, lupus, migraine headaches, porphyria, or thyroid problems. Tell your doctor if you have a history of cancer or serious allergic reactions (such as hereditary angioedema).

• This medicine may increase your risk for the following: Cancer, including breast cancer, especially with long-term use of large dosesHeart attack or dementiaStroke or blood clots, especially if you smoke, you have high blood pressure, high cholesterol, or diabetes, or you are overweight

• Tell your doctor if you have a sudden, severe headache or vision changes while you are taking this medicine. He may want you to have your eyes checked by an eye doctor.

• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Tell any doctor or dentist who treats you that you are taking this medicine. You may need to stop taking it before you have surgery or if you need to be on bedrest.

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Swelling in your face, hands, ankles, or feet

• Yellowing of your skin or the whites of your eyes

• Tell your doctor if you have endometriosis or a history of cancer. Tell your doctor if you have asthma, diabetes, epilepsy, gallbladder, heart, or kidney disease, high or low calcium, lupus, migraine headaches, porphyria, or thyroid problems. Tell your doctor if you have high blood pressure, high cholesterol, a family history of high cholesterol, or a history of liver problems caused by pregnancy or estrogen.

• This medicine may increase your risk for the following: DementiaHeart attack, blood clots, or stroke, especially if you smoke, have diabetes or high cholesterol, or are overweightBreast or ovarian cancerUterine cancer if you take this medicine without a progestin medicine

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

• Stop taking this medicine and check with your doctor immediately if you have a severe headache or sudden loss of vision or vision changes. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

• Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Pelvic exam, breast exam, and mammogram (breast x-ray) may be needed to check for side effects.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Yellow skin or eyes

Premphase interactions

• Some medicines can affect how estrogens work. Tell your doctor if you are taking a blood thinner (such as warfarin), thyroid replacement medicine, or other female hormones.

• This medicine may increase your risk for the following: DementiaHeart attack, blood clots, or stroke, especially if you smoke, have diabetes or high cholesterol, or are overweightBreast or ovarian cancerUterine cancer if you take this medicine without a progestin medicine

• Tell your doctor if you have endometriosis or a history of cancer. Tell your doctor if you have asthma, diabetes, epilepsy, gallbladder, heart, or kidney disease, high or low calcium, lupus, migraine headaches, porphyria, or thyroid problems. Tell your doctor if you have high blood pressure, high cholesterol, a family history of high cholesterol, or a history of liver problems caused by pregnancy or estrogen.

• Stop taking this medicine and check with your doctor immediately if you have a severe headache or sudden loss of vision or vision changes. Your doctor may want you to have your eyes checked by an ophthalmologist (eye doctor).

• Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments. Pelvic exam, breast exam, and mammogram (breast x-ray) may be needed to check for side effects.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Some medicines and foods can affect how this medicine works. Tell your doctor if you are taking any of the following: Carbamazepine, phenobarbitalClarithromycin, erythromycinItraconazole, ketoconazoleRifampinRitonavirSt John's wortThyroid medicine

• Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

• This medicine may increase your risk for the following: Cancer, including breast cancer, especially with long-term use of large dosesHeart attack or dementiaStroke or blood clots, especially if you smoke, you have high blood pressure, high cholesterol, or diabetes, or you are overweight

• Tell your doctor if you have a sudden, severe headache or vision changes while you are taking this medicine. He may want you to have your eyes checked by an eye doctor.

• Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results. Tell any doctor or dentist who treats you that you are taking this medicine. You may need to stop taking it before you have surgery or if you need to be on bedrest.

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.