What is Temodar: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Temodar overview

BRAND NAMES:

  • Temozolomide, Temodar, Temodar

Generic Names:

  • Temozolomide

Uses:

  • Treats brain cancer., Treats brain cancer.

Therapeutic Classes:

  • Antineoplastic Agent, Antineoplastic Agent

Forms:

  • Injectable, Capsule

How it’s taken:

  • By mouth, By injection

What is Temodar used for?

Temodar is a cancer medicine that comes in the form of a powder for injection. It is used along with radiation therapy to treat certain types of brain tumors in adults. Temodar is usually used after other cancer medicines have been used but failed to treat the condition. You should not use Temodar if you are pregnant or plan to become pregnant. Common Temodar side effects may include nausea, vomiting, loss of appetite, skin rash and bruising.

What form(s) does Temodar come in

  • Injectable

  • Capsule

What are common Temodar doses?

  • Capsule 180MG

  • Capsule 250MG

  • Box 1 Capsules

Common Temodar prescriptions

  • Temodar
    1 capsules box

  • Temodar
    100mg capsule

  • Temodar
    140mg capsule

  • Temodar
    180mg capsule

  • Temodar
    20mg capsule

  • Temodar
    250mg capsule

  • Temodar
    5mg capsule

How to take Temodar

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • To help prevent nausea or vomiting, you may try taking this medicine at bedtime on an empty stomach.

  • Swallow the capsule whole with a glass of water. Do not crush, break, chew, or open it.

  • If a capsule breaks open, be careful not to breathe in any medicine or get it on your skin. Wash your skin right away with soap and water if any medicine gets on it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Oral routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions. If you vomit right after you take the medicine, do not take more medicine. Wait until your next scheduled dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • To help prevent nausea or vomiting, you may try taking this medicine at bedtime on an empty stomach.

  • Swallow the capsule whole with a glass of water. Do not crush, break, chew, or open it.

  • Missed dose: Oral routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions. If you vomit right after you take the medicine, do not take more medicine. Wait until your next scheduled dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • If a capsule breaks open, be careful not to breathe in any medicine or get it on your skin. Wash your skin right away with soap and water if any medicine gets on it.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. Each treatment usually takes about 90 minutes.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. Each treatment usually takes about 90 minutes.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

What to do if you miss a dose of Temodar

Temodar contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to temozolomide or dacarbazine (DTIC), or if you are pregnant or breastfeeding.

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to temozolomide or dacarbazine (DTIC), or if you are pregnant or breastfeeding.

Temodar warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Injection routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Women should not get pregnant during treatment and for at least 6 months after treatment ends. Men should not father a child for at least 3 months after treatment ends.

  • Do not breastfeed during treatment and for at least 1 week after the last dose.

  • Tell your doctor if you have kidney disease, liver disease, anemia or any blood cell problems, or any type of infection.

  • This medicine may cause the following problems:Higher risk of pneumoniaHigher risk of other cancersLiver problems

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • If you plan to have children, talk with your doctor before using this medicine. Some men using this medicine have become infertile (unable to have children).

  • Men should not donate semen during treatment and for at least 3 months after the final dose of this medicine.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Oral routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Women should not get pregnant during treatment and for at least 6 months after treatment ends. Men should not father a child for at least 3 months after treatment ends.

  • Do not breastfeed during treatment and for at least 1 week after the last dose.

  • Tell your doctor if you have kidney disease, liver disease, anemia or any blood cell problems, or any type of infection.

  • This medicine may cause the following problems:Higher risk of pneumoniaHigher risk of other cancersLiver problems

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • If you plan to have children, talk with your doctor before using this medicine. Some men using this medicine have become infertile (unable to have children).

  • Men should not donate semen during treatment and for at least 3 months after the final dose of this medicine.

  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Temodar interactions

  • Some medicines can affect how temozolomide works. Tell your doctor if you are also using valproic acid.

  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, anemia or any blood cell problems, or any type of infection.

  • This medicine may cause the following problems:Higher risk of pneumoniaHigher risk of other cancersLiver problems

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Some medicines can affect how temozolomide works. Tell your doctor if you are also using valproic acid.

  • Tell your doctor if you are breastfeeding, or if you have kidney disease, liver disease, anemia or any blood cell problems, or any type of infection.

  • This medicine may cause the following problems:Higher risk of pneumoniaHigher risk of other cancersLiver problems

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Temodar side effects

Serious Side Effects

  • Seizures

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, or red skin rash

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Fever, chills, cough, sore throat, body aches

  • Severe nausea or vomiting

  • Unusual bleeding, bruising, or weakness

  • Severe nausea or vomiting

  • Unusual bleeding, bruising, or weakness

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, or red skin rash

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Fever, chills, cough, sore throat, body aches

  • Seizures

Less Serious Side Effects

  • Hair loss

  • Pain, itching, burning, swelling, redness, or a lump under your skin where the needle is placed

  • Tiredness

  • Headache

  • Mild nausea or vomiting, constipation

  • Mild nausea or vomiting, constipation

  • Tiredness

  • Hair loss

  • Headache

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