What is Cisplatin: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Cisplatin overview

BRAND NAMES:

Generic Names:

  • Cisplatin

Uses:

  • Treats cancer of the bladder, ovaries, or testicles.

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Cisplatin used for?

Cisplatin is an intravenous solution that is used by patients to treat certain cancerous conditions such as ovarian and testicular cancer. It works by reducing the amount of cancer cells in the body.

What form(s) does Cisplatin come in

  • Injectable

What are common Cisplatin doses?

  • Vial 50ML of 50MG/50ML

  • Vial 100ML of 100MG/100ML

  • Vial 200ML of 200MG/200ML

Common Cisplatin prescriptions

  • CISplatin
    50mg solution reconstituted

  • CISplatin
    100ml of 100mg/100ml vial

  • CISplatin
    200ml of 200mg/200ml vial

  • CISplatin
    50ml of 50mg/50ml vial

How to take Cisplatin

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to stay in place for 6 to 8 hours.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Drink extra fluids so you will urinate more often and help prevent kidney problems.

  • Tell your caregiver right away if this medicine gets on your skin or in your eyes, nose, or mouth.

  • This medicine is usually used with other medicines. If you are using a combination of medicines, it is important that you receive each one at the proper time.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Drink extra fluids so you will urinate more often and help prevent kidney problems.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. This medicine must be given slowly, so the needle will have to stay in place for 6 to 8 hours.

  • Tell your caregiver right away if this medicine gets on your skin or in your eyes, nose, or mouth.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • This medicine is usually used with other medicines. If you are using a combination of medicines, it is important that you receive each one at the proper time.

What to do if you miss a dose of Cisplatin

Cisplatin contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to cisplatin, or if you are pregnant.

Cisplatin warnings

  • Injection routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. If you are female and able to get pregnant, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Use an effective form of birth control during treatment and for at least 14 months after the last dose. Male patients with female partners should use an effective form of birth control during treatment and for at least 11 months after the last dose.

  • Do not breastfeed during treatment with this medicine.

  • Tell your doctor if you have kidney disease, liver disease, nerve problems, blood or bone marrow problems, or ear or hearing problems.

  • This medicine may cause the following problems:Kidney problemsNerve problems, including peripheral neuropathyEar or hearing problemsEye problems, including optical neuritis, papilledema, cortical blindnessIncreased risk for other cancers, including leukemiaInjection site reactions

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Injection routeThis medicine could cause infertility. Talk with your doctor before using this medicine if you plan to have children.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Unusual bleeding, bruising, or weakness

Cisplatin interactions

  • Some medicines can affect how cisplatin works. Tell your doctor if you are using medicine that affects your kidneys or ears.

  • Tell your doctor if you are breastfeeding or have any health conditions.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Your doctor will need to check your blood and urine at regular visits while you are using this medicine. You may also need to have hearing tests. Keep all appointments.

  • Injection routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

  • Side effects may appear in between treatments or after you have stopped using this medicine.

Cisplatin side effects

Serious Side Effects

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Unusual bleeding, bruising, tiredness, or weakness

  • Fever, chills, cough, sore throat, body aches

  • Ringing, buzzing, or trouble hearing in one or both ears, dizziness, loss of balance

  • Severe nausea or vomiting

  • Bone or joint pain, pale skin, weight loss, swollen lymph glands in the neck, armpit, groin, or stomach

  • Numbness, tingling, or burning pain in your hands, arms, legs, or feet

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blurred or changes in vision, eye pain

  • Change in how much or how often you urinate, dark urine, lower back or side pain, painful urination, swelling of the feet or lower legs

Less Serious Side Effects

  • Diarrhea, loss of appetite

  • Pain, redness, or swelling where the IV needle is inserted

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.