The prescription antiviral Xofluza is used for the treatment of the flu and for post-exposure prophylaxis against it. It is available in tablet and liquid forms and is taken as a single-dose regimen. Despite only being one dose, the average cost of Xofluza without insurance is $243.08 per 1, 1 x 40mg tablet therapy pack. A Xofluza coupon from SingleCare drops the expense considerably, down to $167.12 for 1, 1 x 40mg tablet therapy pack.
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Prices updated: 09/07/2026
The prescription antiviral Xofluza is used for the treatment of the flu and for post-exposure prophylaxis against it. It is available in tablet and liquid forms and is taken as a single-dose regimen. Despite only being one dose, the average cost of Xofluza without insurance is $243.08 per 1, 1 x 40mg tablet therapy pack. A Xofluza coupon from SingleCare drops the expense considerably, down to $167.12 for 1, 1 x 40mg tablet therapy pack.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Xofluza Retail Price | Xofluza SingleCare Price |
|---|---|---|
| CVS Pharmacy | $201.99 | $197.88 |
| Walmart | $202.60 | $182.79 |
| Walgreens | $249.99 | $182.27 |
| Kroger Pharmacy | $202.49 | $170.12 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
The prescription antiviral Xofluza is used for the treatment of the flu and for post-exposure prophylaxis against it. It is available in tablet and liquid forms and is taken as a single-dose regimen. Despite only being one dose, the average cost of Xofluza without insurance is $243.08 per 1, 1 x 40mg tablet therapy pack. A Xofluza coupon from SingleCare drops the expense considerably, down to $167.12 for 1, 1 x 40mg tablet therapy pack.
Xofluza costs $167.12 for 1, 1 x 40mg tablet therapy pack with a free Xofluza coupon from SingleCare. However, you could pay less depending on your prescription information. Use the dropdown menu above to enter your Rx info (i.e., generic/brand, quantity, dosage, form) to get the most accurate prices of Xofluza with SingleCare near you.
The Xofluza price, when paid completely out-of-pocket without insurance coverage, can be surprising. It can cost $243.08 per 1, 1 x 40mg tablet therapy pack. The reason for the expense is that Xofluza is a brand-name drug without a generic alternative. Nonetheless, you can take a SingleCare coupon along with your prescription to the pharmacy, and the price of Xofluza becomes only $167.12 for 1, 1 x 40mg tablet therapy pack.
Insurance plans may not include Xofluza on their formulary because of the hefty price tag associated with its brand-name-only status. Even if it is covered, Xofluza may require a higher copay than other treatment options, and if the plan has a deductible for prescriptions, some or all of the drug expense could be out-of-pocket. Using our coupon instead of insurance could save you money if Xofluza is not covered or if the copay or deductible exceeds the SingleCare discounted price.
Like private health insurance plans, Medicare plans review pricier drugs like Xofluza. Not every plan will cover it, and the plans that do may require a significant out-of-pocket payment depending on the copay structure and deductible of the plan, as well as what coverage stage a person is in during the year. For some people, a SingleCare coupon for Xofluza may provide savings compared to using their Medicare coverage.
Medicaid coverage for Xofluza varies by state and depends on an individual’s plan details and coverage stage. Unfortunately, it may not be covered, at least not completely. The plans that do have Xofluza on formulary may require a significant out-of-pocket payment in the form of a copay or deductible. Once again, a SingleCare Xofluza coupon can be used instead of Medicaid coverage, and it makes sense to do so when the copay or deductible ends up being more than our price of $167.12 for 1, 1 x 40mg tablet therapy pack.
The active ingredient in Xofluza is baloxavir, but a generic version is not available on the market. Patent protection for the brand Xofluza is expected to last at least until 2036. For that reason, finding discount options for the drug will remain important.
Demand for Xofluza naturally surges during the winter months, when influenza rates are at their peak. The misery of having the flu need not be compounded by overpaying for treatment. A SingleCare Xofluza coupon without insurance can bring the price down 30% at local pharmacies. As a brand-name drug, Xofluza may also offer manufacturer-based savings opportunities. The pharmaceutical company Genentech offers a coupon for use by eligible patients, as well as a cash pay price when purchased at a limited number of locations. Keep in mind that restrictions apply to these manufacturer programs.
Oseltamavir, the generic form of Tamiflu, is a commonly used antiviral for treating influenza. Its expense is typically lower than {{drug} prices, and insurance coverage is usually better. Oseltamivir is prescribed as a five-day course, so single-dose Xofluza certainly has it beat for convenience.
You can use SingleCare coupons at most major pharmacies and grocery stores, including Walgreens, Kroger, Walmart, CVS, Safeway, and more. Just text, email, print, or save your free Xofluza coupon to your digital wallet and show a pharmacist at checkout.
Chad Shaffer, MD, earned his medical doctorate from Penn State University and completed a combined Internal Medicine and Pediatrics residency at the University of Pittsburgh Medical Center and Children’s Hospital of Pittsburgh. He is board certified by the American Board of Internal Medicine and the American Board of Pediatrics. He has provided full-service primary care to all ages for over 15 years, building a practice from start up to over 3,000 patients. His passion is educating patients on their health and treatment, so they can make well-informed decisions.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved