Advate is a brand-name prescription drug that provides a blood-clotting protein that is missing in people with hemophilia A, a condition in which the blood does not have the ability to form blood clots and stop a bleeding incident. Advate is administered as an intravenous infusion during a bleeding episode to control bleeding or it is administered before medical or dental procedures to prevent a bleeding episode. Advate costs $15,507.78 at full price. A SingleCare Advate coupon reduces that price to $7.79. Advate is not purchased in pharmacies. Ask the clinic or hospital where you receive your Advate injection if they will accept a SingleCare Advate coupon; you could pay $7.79.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 04/16/2026
Advate is a brand-name prescription drug that provides a blood-clotting protein that is missing in people with hemophilia A, a condition in which the blood does not have the ability to form blood clots and stop a bleeding incident. Advate is administered as an intravenous infusion during a bleeding episode to control bleeding or it is administered before medical or dental procedures to prevent a bleeding episode. Advate costs $15,507.78 at full price. A SingleCare Advate coupon reduces that price to $7.79. Advate is not purchased in pharmacies. Ask the clinic or hospital where you receive your Advate injection if they will accept a SingleCare Advate coupon; you could pay $7.79.
Advate is a brand-name prescription drug that provides a blood-clotting protein that is missing in people with hemophilia A, a condition in which the blood does not have the ability to form blood clots and stop a bleeding incident. Advate is administered as an intravenous infusion during a bleeding episode to control bleeding or it is administered before medical or dental procedures to prevent a bleeding episode. Advate costs $15,507.78 at full price. A SingleCare Advate coupon reduces that price to $7.79. Advate is not purchased in pharmacies. Ask the clinic or hospital where you receive your Advate injection if they will accept a SingleCare Advate coupon; you could pay $7.79.
Advate costs around $15,507.78 for uninsured customers. With a SingleCare Advate coupon, you will pay $7.79 per 3, 4000unit solution reconstituteds for the same prescription of Advate if the clinic or hospital where you receive Advate injections will accept a SingleCare savings card.
Your copay for Advate with insurance will vary depending on your plan and the price charged for Advate by the clinic where you get your injection. However, Advate will usually be covered by your health insurance as a medical benefit similar to a blood transfusion rather than a prescription drug benefit. Ask the hospital or clinic where you receive Advate injections if they will accept a SingleCare Advate coupon; you could pay $7.79.
Advate is usually not covered under Medicare Part D and Medicare Advantage prescription drug plans, but is covered under Medicare Part B as a medical benefit. Ask the hospital or clinic where you receive Advate injections if they will accept a SingleCare savings card; you could pay $7.79.
Advate is a brand-name prescription drug that is not available in a generic version. Other brand-name antihemophilic factor intravenous injections include Adynovate, Helixate, Kogenate, Kovaltry, and Recombinant. If you have any questions about these other brand-name antihemophilic factor injections, consult the SingleCare website or app. You'll also find valuable savings coupons for all of these treatments.
Advate is a brand-name prescription drug that provides a blood-clotting protein called factor VIII that is missing in people with hemophilia A, a condition in which the blood does not have the ability to form blood clots and stop a bleeding incident. Advate is administered as an intravenous infusion during a bleeding episode to control bleeding or before medical or dental procedures to prevent a bleeding episode.
Blood clots are complex processes in which blood platelets, small blood cells, are “glued” together to form a patch over any damage to a blood vessel. Blood clotting has several steps called the “coagulation cascade.” These are governed by proteins, called factors, which are numbered by their place in the blood clotting process. Factor VIII, called antihemophilic factor, is responsible for producing the next proteins in the process (factor IX and factor X) that eventually end up producing the fibrous “glue” that forms blood clots. Patients with hemophilia A do not produce enough factor VIII, so the coagulation cascade stops at factor VII and they are unable to form blood clots.
Advate is an intravenous injection of factor VIII proteins (antihemophilic factor) that is only used during a bleeding episode or prior to medical or dental procedures that will cause bleeding. It is meant to be administered only by a physician experienced in hemophilia A.
Nearly all patients who take Advate will experience injection site reactions, such as pain, irritation, swelling, redness, and bruising. Other common side effects of Advate include, but are not limited to, headache, fever, chills, cough, sore throat, cold symptoms, nausea, vomiting, joint pain, sweating, swelling, hot flashes, rash, and runny or stuffy nose. Serious side effects include limb injury and upper respiratory tract infections.
Allergic reactions are very rare. Advate is always administered by a healthcare professional in an environment in which the patient is heavily monitored, so allergic reactions will be immediately responded to.
This is not a complete list of possible side effects. Consult with your prescribing physician and pharmacist about possible side effects before starting on Advate.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved