What is Amytal Sodium? Uses, warnings & side effects

Updated May 14, 2025  •  Published Feb 14, 2024

Amytal Sodium overview

BRAND NAMES:

  • Amytal Sodium

Generic Names:

  • Amytal Sodium

Uses:

  • Treats insomnia and also makes you feel sleepy before surgery. This is a barbiturate.

Therapeutic Classes:

  • Anticonvulsant, Sedative

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Amytal Sodium used for?

What form(s) does Amytal Sodium come in?

  • Injectable

What are common Amytal Sodium dosages?

  • Solution Reconstituted 500mg

How to take Amytal Sodium

  • Injection routeA nurse or other health provider will give you this medicine.

  • This medicine is given through a needle placed in one of your veins or as a shot into a muscle.

What to do if you miss a dose of Amytal Sodium

Amytal Sodium contraindications - Who shouldn't take Amytal Sodium?

  • This medicine is not right for everyone. Do not receive this medicine if you had an allergic reaction to barbiturates, you are pregnant, or you have porphyria or certain types of liver disease or lung disease.

Amytal Sodium warnings

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.

  • Tell your doctor if you are breastfeeding, you have liver disease or severe pain in any part of your body, or you have severe depression or a history of drug addiction.

  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

  • This medicine may make you drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

  • Lightheadedness or fainting

  • Pale skin or lips

  • Slow heartbeat

  • Trouble breathing

Amytal Sodium interactions & what to avoid when taking Amytal Sodium

  • Many medicines can interact with amobarbital. Tell your doctor about all other medicines you are taking, especially the following: Antibiotics Blood thinner, such as warfarinGriseofulvinHormones, such as estradiol, estrone, or progesteroneMAO inhibitor (MAOI)Seizure medicineSteroid medicine, such as hydrocortisone, methylprednisolone, prednisone

  • Do not drink alcohol while you are using this medicine.

  • This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

  • This medicine may make you drowsy. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

Amytal Sodium side effects - How does Amytal Sodium make you feel?

Serious Side Effects

  • Pale skin or lips

  • Trouble breathing

  • Lightheadedness or fainting

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Abnormal behavior, drowsiness, or confusion

  • Anxiety or agitation

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Slow heartbeat

Less Serious Side Effects

  • Dizziness or trouble sleeping

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Mild nausea, vomiting, or constipation

  • Fever or headache

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