Brixadi is a brand-name prescription drug used to treat severe opioid use disorder (OUD) as part of a treatment plan that includes counseling and psychosocial support. It works as a partial opioid agonist to help reduce cravings and withdrawal symptoms. Brixadi is given as a subcutaneous extended-release injection monthly or weekly by a healthcare provider. The average retail price of Brixadi is $2,351.47 for 1, 128mg/0.36ml, 1ml syringe syringe kit. However, with a SingleCare Brixadi coupon, you could pay as little as $1,738.66 for 1, 128mg/0.36ml, 1ml syringe syringe kit if the hospital or clinic where you receive the injection accepts it.
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Prices updated: 01/19/2026
Brixadi is a brand-name prescription drug used to treat severe opioid use disorder (OUD) as part of a treatment plan that includes counseling and psychosocial support. It works as a partial opioid agonist to help reduce cravings and withdrawal symptoms. Brixadi is given as a subcutaneous extended-release injection monthly or weekly by a healthcare provider. The average retail price of Brixadi is $2,351.47 for 1, 128mg/0.36ml, 1ml syringe syringe kit. However, with a SingleCare Brixadi coupon, you could pay as little as $1,738.66 for 1, 128mg/0.36ml, 1ml syringe syringe kit if the hospital or clinic where you receive the injection accepts it.
Brixadi is a brand-name prescription drug used to treat severe opioid use disorder (OUD) as part of a treatment plan that includes counseling and psychosocial support. It works as a partial opioid agonist to help reduce cravings and withdrawal symptoms. Brixadi is given as a subcutaneous extended-release injection monthly or weekly by a healthcare provider. The average retail price of Brixadi is $2,351.47 for 1, 128mg/0.36ml, 1ml syringe syringe kit. However, with a SingleCare Brixadi coupon, you could pay as little as $1,738.66 for 1, 128mg/0.36ml, 1ml syringe syringe kit if the hospital or clinic where you receive the injection accepts it.
Without insurance, the price of Brixadi can vary, as it’s not available for purchase in retail pharmacies and is typically given in a clinic or hospital. The average cost per month is $2,351.47 for 1, 128mg/0.36ml, 1ml syringe syringe kit. To help manage these costs, SingleCare offers a discount card that may help reduce the price to as low as $1,738.66 for 1, 128mg/0.36ml, 1ml syringe syringe kit.
The cost of Brixadi with insurance can vary greatly depending on the details of your insurance plan. If a healthcare professional administers Brixadi in a clinic or healthcare facility, it may be billed under medical benefits as part of the healthcare visit. This would typically be part of the coverage for outpatient services, which can include treatments received in a healthcare provider's office or clinic. However, there may still be a copay or deductible.
Medicare coverage for Brixadi depends on your specific Medicare plan. Coverage would typically fall under Medicare Part B if it is administered in an outpatient setting like a health clinic. To find out if your plan covers Brixadi, check with your plan directly. Even with Medicare, SingleCare's Brixadi coupons could offer a lower price, sometimes saving you more than your Medicare plan. The lowest price available with a SingleCare coupon can be $1,738.66 for 1, 128mg/0.36ml, 1ml syringe syringe kit.
Brixadi is a medication approved by the FDA to treat severe opioid use disorder. It is intended for those who have already begun treatment with a transmucosal buprenorphine-containing product and need a long-term medication to prevent relapse.
As an opioid partial agonist, Brixadi helps to alleviate cravings and withdrawal symptoms without producing the full opioid effect. Brixadi works by binding to the same receptors in the brain as other opioids but does not fully activate these receptors, which can help reduce the risk of misuse. It is part of a class of drugs known as partial opioid agonists.
Currently, no generic version of Brixadi is available. Brixadi is a brand-name medication manufactured by Braeburn, Inc. Since it's a brand-name drug, the cost might be higher than generic medications. However, the Brixadi copay savings program and SingleCare discount cards may help patients save on their prescriptions.
Most medications have side effects, and Brixadi is no exception. Common side effects may include:
Headache
Nausea
Constipation
Injection site reactions
Urinary tract infection
Serious side effects can occur, including adrenal insufficiency, a life-threatening allergic reaction, and liver problems. Brixadi also carries a boxed warning for the risk of serious harm or death if injected intravenously. Therefore, Brixadi is only available through a special REMS program (Risk Evaluation and Mitigation Strategy), which ensures that the benefits of the drug outweigh its risks,
If you experience any severe side effects or signs of an opioid overdose, seek medical help immediately. Always consult your healthcare provider for medical advice and discuss any concerns or questions regarding your treatment plan and potential side effects. The medication guide and full prescribing information may also provide a comprehensive list of potential side effects.
Brixadi is administered as a subcutaneous injection by a healthcare professional. This means it is injected under the skin, typically in the abdominal area. The extended-release formulation allows for monthly or weekly dosing, which can be more convenient than daily medications. It's important that Brixadi is only administered by a healthcare provider who is enrolled in the REMS (Risk Evaluation and Mitigation Strategy) program, which ensures the safe use of certain medications that can have serious risks.
Yes, Brixadi is classified as a Schedule III controlled substance. This means that while it has an accepted medical use, it also has the potential for abuse and dependence. Due to this, the handling, prescribing, and dispensing of Brixadi are subject to strict regulations to prevent misuse and diversion.
Both Brixadi and Sublocade are brand-name buprenorphine products used to treat severe opioid use disorder. The main difference lies in their formulations and dosing schedules. Brixadi can be given as a weekly or monthly extended-release injection, while Sublocade is only recommended as a monthly injection. Additionally, Brixadi may be administered in various locations such as the buttock, thigh, stomach, or upper arm, whereas Sublocade is only injected into the abdomen.
Gerardo Sison, Pharm.D., graduated from the University of Florida. He has worked in both community and hospital settings, providing drug information and medication therapy management services. As a medical writer, he hopes to educate and empower patients to better manage their health and navigate their treatment plans.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved