What is Chlorpromazine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Chlorpromazine overview

BRAND NAMES:

Generic Names:

  • Chlorpromazine Hcl

Uses:

  • Treats bipolar disorder, schizophrenia, tetanus, porphyria, severe hiccups, and severe nausea and vomiting. Also used to reduce anxiety before surgery. This medicine is a phenothiazine.

Therapeutic Classes:

  • Antiemetic, Antipsychotic

Forms:

  • Tablet, Long Acting Capsule, Liquid

How it’s taken:

  • By mouth

What is Chlorpromazine used for?

What form(s) does Chlorpromazine come in

  • Tablet

  • Long Acting Capsule

  • Liquid

What are common Chlorpromazine doses?

  • Tablet 10MG

  • Tablet 25MG

  • Tablet 50MG

  • Tablet 100MG

  • Tablet 200MG

  • Ampule 1ML of 25MG/ML

  • Ampule 2ML of 50MG/2ML

Common Chlorpromazine prescriptions

  • chlorproMAZINE HCl
    1ml of 25mg/ml ampule

  • chlorproMAZINE HCl
    2ml of 50mg/2ml ampule

  • chlorproMAZINE HCl
    100mg tablet

  • chlorproMAZINE HCl
    10mg tablet

  • chlorproMAZINE HCl
    200mg tablet

  • chlorproMAZINE HCl
    25mg tablet

  • chlorproMAZINE HCl
    50mg tablet

  • chlorproMAZINE HCl
    2ml of 50mg/2ml vial

How to take Chlorpromazine

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Do not crush or chew the tablet or capsule.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Do not crush or chew the tablet or capsule.

What to do if you miss a dose of Chlorpromazine

Chlorpromazine contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to chlorpromazine or any other phenothiazine drug.

Chlorpromazine warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have asthma, emphysema, breast cancer, trouble urinating, glaucoma, seizures, or a bone marrow or blood disorder. Tell your doctor if you have heart, kidney, or liver disease, or lupus.

  • This medicine may cause drowsiness or affect your sight. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

  • This medicine may cause the following problems: Neuroleptic malignant syndrome (NMS)Tardive dyskinesia

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

Chlorpromazine interactions

  • Many other drugs can interact with chlorpromazine. Tell your doctor about all other medicines you are taking, including the following:Blood thinner, such as warfarin Blood pressure medicine, such as atenolol, guanethidine, metoprolol, propranololDiuretic (water pill), such as hydrochlorothiazideLithiumMedicine to treat muscle spasms, such as atropineSeizure medicine

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • This medicine may cause the following problems: Neuroleptic malignant syndrome (NMS)Tardive dyskinesia

  • This medicine may make your skin more sensitive to sunlight. Wear sunscreen. Do not use sunlamps or tanning beds.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Chlorpromazine side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Drowsiness or dizziness, confusion

  • Fast or uneven heartbeat

  • Jerky muscle movement you cannot control (often in your face, tongue, or jaw)

  • Seizures

Less Serious Side Effects

  • Agitation, restlessness, or insomnia

  • Weakness