Learn more about diclofenac-misoprostol
Diclofenac-Misoprostol is a combination drug containing a nonsteroidal anti-inflammatory drug (NSAID) and prostaglandin-1 (PGE1) analog. Diclofenac sodium is an NSAID while misoprostol is a PGE1 analog. This generic prescription drug is used to treat rheumatoid arthritis and osteoarthritis in people who are at high risk of stomach or duodenal ulcers. The average cash price of Diclofenac-Misoprostol is $242.46 for 60, 75mg/0.2mg tablets, but you could pay only $50.16 for 60, 75mg/0.2mg tablets when you use a SingleCare discount card.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/18/2025
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About Diclofenac-Misoprostol
Diclofenac-Misoprostol is a combination drug containing a nonsteroidal anti-inflammatory drug (NSAID) and prostaglandin-1 (PGE1) analog. Diclofenac sodium is an NSAID while misoprostol is a PGE1 analog. This generic prescription drug is used to treat rheumatoid arthritis and osteoarthritis in people who are at high risk of stomach or duodenal ulcers. The average cash price of Diclofenac-Misoprostol is $242.46 for 60, 75mg/0.2mg tablets, but you could pay only $50.16 for 60, 75mg/0.2mg tablets when you use a SingleCare discount card.
Learn more about diclofenac-misoprostol
Diclofenac-Misoprostol Price History & Information
Price History for Diclofenac-Misoprostol (Generic) & Arthrotec (Brand)
60 count, tablet delayed release, 75-0.2mgOur price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
Average 1-Month Prices for Diclofenac-Misoprostol (Generic) & Arthrotec (Brand)
60 count, tablet delayed release, 75-0.2mg| Pharmacy | Diclofenac-Misoprostol Retail Price | Diclofenac-Misoprostol SingleCare Price |
|---|---|---|
| CVS Pharmacy | $190.20 | $53.40 |
| Walmart | $195.00 | $89.40 |
| Walgreens | $208.20 | $76.80 |
| Kroger Pharmacy | $218.28 | $89.40 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
About Diclofenac-Misoprostol
Diclofenac-Misoprostol is a combination drug containing a nonsteroidal anti-inflammatory drug (NSAID) and prostaglandin-1 (PGE1) analog. Diclofenac sodium is an NSAID while misoprostol is a PGE1 analog. This generic prescription drug is used to treat rheumatoid arthritis and osteoarthritis in people who are at high risk of stomach or duodenal ulcers. The average cash price of Diclofenac-Misoprostol is $242.46 for 60, 75mg/0.2mg tablets, but you could pay only $50.16 for 60, 75mg/0.2mg tablets when you use a SingleCare discount card.
Diclofenac-Misoprostol FAQs
How much does Diclofenac-Misoprostol cost without insurance?
The average retail cost of Diclofenac-Misoprostol without health insurance is $242.46 for 60, 75mg/0.2mg tablets. The actual retail price can vary depending on the quantity and dosage prescribed. You may be able to save by using a SingleCare Diclofenac-Misoprostol coupon to pay just $50.16 for 60, 75mg/0.2mg tablets.
How much does Diclofenac-Misoprostol cost with insurance?
Health insurance plans may or may not cover Diclofenac-Misoprostol. The cost of Diclofenac-Misoprostol with insurance coverage can vary depending on the plan. Reach out to your insurance company or pharmacist for help determining your insurance coverage and potential copay. If your insurance does not cover Diclofenac-Misoprostol, you may be able to use SingleCare to get discounts on Diclofenac-Misoprostol at participating pharmacies.
What is the brand name of Diclofenac-Misoprostol?
The brand name of Diclofenac-Misoprostol is Arthrotec, which is manufactured by Pfizer. Diclofenac-Misoprostol is a generic medication manufactured by various companies like Sandoz, Amneal, and Actavis.
What is Diclofenac-Misoprostol?
Diclofenac-Misoprostol is a combination prescription drug used to treat signs and symptoms of osteoarthritis and rheumatoid arthritis. It contains an NSAID (diclofenac sodium) and a PGE-1 analog (misoprostol). Diclofenac helps relieve pain and inflammation from arthritis while misoprostol helps protect the stomach lining and prevent ulcers.
Diclofenac-Misoprostol is available as a delayed-release tablet. It is usually taken two to four times daily. The exact dosage will depend on the condition being treated.
Tell your doctor about any medical conditions you have or other medications you may be taking before starting treatment with Diclofenac-Misoprostol. This medication should only be used as prescribed by a healthcare provider.
What are the side effects of Diclofenac-Misoprostol?
The most common side effects of Diclofenac-Misoprostol are headache, indigestion, nausea, vomiting, diarrhea, stomach pain, gas, constipation, and dizziness. Serious side effects of Diclofenac-Misoprostol include fetal toxicity, abortion, and birth defects. The use of Diclofenac-Misoprostol can also increase the risk of heart attacks and strokes, as well as gastrointestinal ulcers. Other serious side effects of Diclofenac-Misoprostol include high blood pressure, liver problems, kidney problems, allergic reactions, skin reactions, and heart problems.
This is not a complete list of side effects. Discuss other side effects, warnings, and precautions with a healthcare provider before taking this drug.
Where are Diclofenac-Misoprostol coupons from SingleCare accepted?
SingleCare is accepted at most national pharmacies and grocers, including the following:
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