Arthrotec is a combination prescription medication used to treat osteoarthritis and rheumatoid arthritis. Arthrotec works to reduce substances in the body that cause pain and inflammation. The generic version of Arthrotec is diclofenac sodium and misoprostol tablets. Without insurance or coupons, you could spend as much as $657.25 for Arthrotec. You can reduce your Arthrotec price to $80.17 with a SingleCare Arthrotec coupon. Our free coupons are accepted at participating pharmacies throughout the United States.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
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Prices updated: 05/14/2026
Arthrotec is a combination prescription medication used to treat osteoarthritis and rheumatoid arthritis. Arthrotec works to reduce substances in the body that cause pain and inflammation. The generic version of Arthrotec is diclofenac sodium and misoprostol tablets. Without insurance or coupons, you could spend as much as $657.25 for Arthrotec. You can reduce your Arthrotec price to $80.17 with a SingleCare Arthrotec coupon. Our free coupons are accepted at participating pharmacies throughout the United States.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Arthrotec Retail Price | Diclofenac-Misoprostol Retail Price | Diclofenac-Misoprostol SingleCare Price |
|---|---|---|---|
| CVS Pharmacy | $627.00 | $190.20 | $43.80 |
| Walmart | - | $108.60 | $90.60 |
| Walgreens | - | $209.40 | $45.00 |
| Kroger Pharmacy | - | $205.67 | $89.40 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
Arthrotec is a combination prescription medication used to treat osteoarthritis and rheumatoid arthritis. Arthrotec works to reduce substances in the body that cause pain and inflammation. The generic version of Arthrotec is diclofenac sodium and misoprostol tablets. Without insurance or coupons, you could spend as much as $657.25 for Arthrotec. You can reduce your Arthrotec price to $80.17 with a SingleCare Arthrotec coupon. Our free coupons are accepted at participating pharmacies throughout the United States.
Arthrotec can cost around $657.25 per 60, 75mg/0.2mg tablets, depending on the pharmacy. There are a few ways to save money. To reduce the cost of Arthrotec, print our free Arthrotec discount card and pay our lowest price of $80.17 for your Arthrotec prescription refills. Our Arthrotec coupons can be redeemed at any CVS Pharmacy, Walmart, Kroger, and Walgreens in the United States.
The average cost of Arthrotec with insurance tends to vary based on the type of health insurance plan you are enrolled in and the level of benefits you are entitled to. You may need to contact your insurance provider to get the exact cost of Arthrotec and how much you will copay for your Arthrotec prescription. However, with SingleCare, you could pay our lowest price of $80.17 when you use our prescription discount card. Your cost with a SingleCare Arthrotec discount card may be cheaper than what you would pay with your insurance. You can compare prices when visiting any SingleCare participating pharmacy.
Arthrotec is not generally covered by Medicare. Fortunately, you may be able to save as much as 80% on the cost of your prescription drugs with a SingleCare prescription savings card. With our discount card, you pay $80.17 for your Arthrotec refills at your local pharmacy. You may also be able to save money by using the generic version of Arthrotec, which may be covered by Medicare.
Arthrotec is a brand-name prescription drug that is manufactured by Pfizer, Inc. Diclofenac sodium and misoprostol tablet is the generic version of Arthrotec.
Arthrotec is a combination-prescription medication that is used to treat osteoarthritis and rheumatoid arthritis. It contains diclofenac, a nonsteroidal anti-inflammatory drug (NSAID) that works by reducing substances in the body that cause pain and inflammation. The second active ingredient, misoprostol decreases stomach acid and replaces protective substances in the stomach that are reduced. The combination of both drugs helps to relieve symptoms of arthritis in patients who may develop stomach from taking nonsteroidal anti-inflammatory drugs.
Do not use Arthrotec if you are allergic to any of its ingredients. If you are pregnant do not use this medication as some ingredients can cause birth defects, miscarriage, premature labor, or rupture of the uterus.
Before taking Arthrotec tell your doctor about any other medical conditions you may have, including if you have a history of asthma or severe allergic reactions to NSAIDs, liver or kidney disease, heart attack, stroke, stomach ulcers or bleeding, or if you are scheduled for heart surgery such as a coronary artery bypass graft. You should also tell your doctor about all the medications you are taking including all prescription medications, over-the-counter medicines, and herbal supplements. If you are taking antidepressants, oral diabetes medications, blood thinners, other NSAIDs, and steroid medications, you need to tell your doctor.
You should use Arthrotec exactly as prescribed by your doctor. Follow all directions on your prescription label but do not take Arthrotec larger amounts or for longer than your doctor recommends. You can take Arthrotec with food or milk which can help to lessen stomach upset. Do not share your medication with anyone.
Keep Arthrotec out of the reach of children and pets.
Common side effects of Arthrotec include heartburn, indigestion, stomach pain, gas, nausea or vomiting, diarrhea, constipation, and abnormal vaginal bleeding.
Call your doctor immediately if you get any serious side effects such as black or tarry stools, bleeding or crusting sores on the lips, blood in the urine, bruises or red spots on the skin, chest pain, confusion, convulsions, disorientation, and fainting.
This is not a complete list of all the possible side effects of Arthrotec and others can occur. You can talk to your doctor about any concerns you may have about this medication to ensure Arthrotec is right for you. You can also report any negative side effects to the FDA.
SingleCare is accepted at most national pharmacies and grocers, including the following:
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved