What is Erythrocin Lactobionate: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Erythrocin Lactobionate overview

BRAND NAMES:

  • Erythrocin Lactobionate

Generic Names:

  • Erythrocin Lactobionate

Uses:

  • Treats infections. Also helps prevent heart infections and rheumatic fever. This medicine is a macrolide antibiotic.

Therapeutic Classes:

  • Antibiotic

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Erythrocin Lactobionate used for?

What form(s) does Erythrocin Lactobionate come in

  • Injectable

What are common Erythrocin Lactobionate doses?

  • Solution Reconstituted 500MG

Common Erythrocin Lactobionate prescriptions

  • Erythrocin Lactobionate
    500mg solution reconstituted

How to take Erythrocin Lactobionate

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

What to do if you miss a dose of Erythrocin Lactobionate

Erythrocin Lactobionate contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to erythromycin.

Erythrocin Lactobionate warnings

  • Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • This medicine may cause the following problems: Liver problemsHeart rhythm problemsInfantile hypertrophic pyloric stenosis

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, heart problems, heart rhythm problems, or myasthenia gravis.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Severe diarrhea, stomach cramps, fever

Erythrocin Lactobionate interactions

  • This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine.

  • Some medicines can affect how erythromycin works. Tell your doctor if you are using any of the following: Alfentanil, amlodipine, bromocriptine, carbamazepine, cimetidine, colchicine, cyclosporine, digoxin, diltiazem, disopyramide, eszopiclone, hexobarbital, phenytoin, sildenafil, theophylline, valproate, verapamil, zopicloneAllergy medicineBenzodiazepine medicine (including midazolam, triazolam)Blood thinner (including warfarin)

  • You should not receive this medicine if you are using astemizole, cisapride, dihydroergotamine, ergotamine, pimozide, terfenadine, or statin medicine (including lovastatin or simvastatin).

Erythrocin Lactobionate side effects

Serious Side Effects

  • Hearing loss

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Fast, pounding, or uneven heartbeat

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Severe diarrhea, stomach cramps, fever

Less Serious Side Effects

  • Pain, itching, swelling, or a lump under your skin where the needle is placed

  • Mild diarrhea