What is Excedrin PM: Uses, Warnings & Interactions

Place the oral powder on your tongue, and then take a drink of water or another liquid. You may also put the powder into a glass of water or other liquid, stir it, and then drink it.

Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

This medicine contains acetaminophen. Read the labels of all other medicines you are using to see if they also contain acetaminophen, or ask your doctor or pharmacist. Do not use more than 4 grams (4,000 milligrams) total of acetaminophen in one day.

Follow the instructions on the medicine label if you are using this medicine without a prescription.

Your doctor will tell you how much medicine to use. Do not use more than directed.

Ask your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

You should not use this medicine if you have had an allergic reaction to acetaminophen (Tylenol®), or to diphenhydramine (Benadryl®). Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years old. Using these medicines in very young children might cause serious or possibly life-threatening side effects.

This medicine may make you drowsy. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Do not give this medicine to anyone under 12 years of age, unless a doctor tells you to.

Make sure your doctor knows if you are pregnant or breast feeding, or if you have glaucoma, kidney problems, or liver problems. Tell your doctor if you have a history of breathing problems such as asthma or COPD (emphysema or chronic bronchitis). Make sure your doctor knows if you have trouble urinating due to an enlarged prostate gland. Tell your doctor if you drink alcohol on a regular basis. Make sure your doctor knows if you have had an allergic reaction to any antihistamine, and about any other health problems you may have.

Do not use this medicine for more than 10 days. Do not use this medicine to treat fever for more than 3 days, unless a doctor tells you to do so. If you have trouble sleeping that lasts for longer than 2 weeks, stop using this medicine and talk to your doctor.

Do not use this medicine for more than 10 days. Do not use this medicine to treat fever for more than 3 days, unless a doctor tells you to do so. If you have trouble sleeping that lasts for longer than 2 weeks, stop using this medicine and talk to your doctor.

Do not drink alcohol while you are using this medicine. Acetaminophen taken with alcohol can increase your risk of damage to your liver. If you regularly drink three or more alcoholic drinks every day, do not take any medicines that contain acetaminophen without asking your doctor.

Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

Do not also use other medicines that contain acetaminophen or diphenhydramine, including topical (skin) medicine. You may be getting more than a safe amount of these medicines.