What is Jatenzo: Uses, Warnings & Interactions
Jatenzo is a brand-name prescription testosterone capsule used for testosterone replacement therapy in men with low testosterone. Jatenzo capsules are taken with food twice daily. Regularly scheduled blood tests are required to make sure the doses are correct. Men should also check their blood pressure regularly when taking this drug.
Jatenzo overview
BRAND NAMES:
Jatenzo
Generic Names:
Testosterone undecanoate
Uses:
Treats low testosterone
Therapeutic Classes:
Androgen
Forms:
Capsule
How it’s taken:
By mouth
What is Jatenzo used for?
Jatenzo is an orally-dosed testosterone product FDA-approved to treat low testosterone in men who have been diagnosed with testicular failure (primary hypogonadism) or problems with the pituitary gland or hypothalamus (hypogonadotropic hypogonadism).
What form(s) does Jatenzo come in
Capsule
158 mg
198 mg
237 mg
What are common Jatenzo doses?
For low testosterone: 158–396 mg twice daily
Common Jatenzo prescriptions
Jatenzo
158mg capsuleJatenzo
198mg capsuleJatenzo
237mg capsule
How to take Jatenzo
Follow all the prescriber’s instructions when taking Jatenzo.
Please read the Medication Guide that comes with this medication.
Take two doses daily—once in the morning, and once in the evening.
Take Jatenzo capsules with food.
Swallow the capsule whole with a drink of water. Do not crush, break, or chew it.
Store Jatenzo capsules in a dry place at room temperature.
What to do if you miss a dose of Jatenzo
Take the missed dose as soon as possible.
Skip the missed dose if it’s almost time for the next dose.
Take the next dose as usual.
Do not take an extra capsule to make up for a missed dose.
Jatenzo contraindications
Jatenzo is not safe for everyone to take.
Do not take Jatenzo if you have:
Breast cancer
Prostate cancer
Known sensitivities to testosterone undecanoate
Jatenzo is also contraindicated for use in pregnant women.
Jatenzo warnings
Tell other healthcare professionals providing treatment that you are taking Jatenzo.
The prescriber requires regular checkups and blood tests to adjust doses, monitor treatment, and check for side effects. Keep all appointments.
Men are advised to regularly check their blood pressure. Tell the prescriber if blood pressure gets too high.
Before starting Jatenzo, tell the prescriber about all your medical conditions, particularly:
High blood pressure
Heart problems
A history of heart attack or stroke
High red blood cell counts
Trouble urinating because of an enlarged prostate
Liver problems
Kidney problems
Sleep apnea
A history of mental health problems, including suicidal thoughts, depression, anxiety, or mood disorder
Jatenzo can cause serious problems, including:
Blood clots in the legs or lungs
High red blood cell counts
High blood pressure
Worsening of enlarged prostate
Increased risk of prostate cancer
Liver problems, including liver tumors
Edema
Worsening of sleep apnea
High calcium
Low thyroid hormone levels
Lowered sperm counts
Development of female breasts
New or worsening depression
Suicidal thoughts and behaviors
Tell the prescriber about any changes in the status of your health when taking Jatenzo.
Testosterone supplements have a high potential for abuse.
High doses can cause serious heart and psychological problems.
Do not increase the dose or take capsules more often than prescribed.
Do not take anabolic steroids when taking Jatenzo.
Women should not take Jatenzo.
Jatenzo interactions
Before starting Jatenzoi, tell the prescribing clinician about all prescription drugs, over-the-counter medications, and supplements regularly taken, particularly:
Insulin
Blood thinners
Corticosteroids
Drugs that increase blood pressure, such as stimulants and cold medicines
Do not use anabolic steroids while taking Jatenzo.
Men taking blood pressure medications may need to have their dose adjusted or be switched to a different blood pressure drug.
Tell other healthcare professionals about Jatenzo before they prescribe new medications.
Jatenzo side effects
Serious side effects
Talk to the prescriber if you notice any signs or symptoms of a possible serious side effect, including:
Sudden pain in your lower leg (calf) that won’t go away
Numbness or weakness on one side of your body, sudden or severe headache, sudden vomiting, problems with walking, speech, or eyesight
Sharp, sudden chest pain, chest tightness, trouble breathing, coughing up blood
Swelling of the leg or foot
Enlarged or painful breasts
Yellow skin or eyes, fatigue, nausea
Changes in urination, difficulty urinating, frequent urination, and urine accidents
Breathing problems while asleep
Unusual moods or behaviors, sudden mood changes, thoughts of hurting yourself
Allergic reaction: Itching, skin rash, hives, swelling of the face, mouth, tongue, or neck, trouble breathing
Some of the serious side effects of Jatenzo may not have clinical signs, so regular doctor’s visits are required to spot these problems:
High red blood cell counts
High blood pressure
High cholesterol or fats
Less serious side effects
Diarrhea
Indigestion
Burping
Nausea
Headache
Find more information about testosterone side effects here.
Sources:
Aveed drug summary, Prescriber’s Digital Reference (PDR)
Jatenzo, Tolmar, Inc.
Jatenzo testosterone undecanoate capsules prescribing information, DailyMed (NIH National Library of Medicine)
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