What is Levobunolol: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Levobunolol overview

BRAND NAMES:

  • Betagan

Generic Names:

  • Levobunolol Hcl

Uses:

  • Lowers pressure inside the eye caused by glaucoma or hypertension in the eye. This medicine is a beta blocker.

Therapeutic Classes:

  • Antiglaucoma

Forms:

  • Drop, Liquid

How it’s taken:

  • Into the eye

What is Levobunolol used for?

What form(s) does Levobunolol come in

  • Drop

  • Liquid

What are common Levobunolol doses?

  • Bottle 5ML of 0.5%

Common Levobunolol prescriptions

  • Levobunolol HCl
    10ml of 0.5% bottle

  • Levobunolol HCl
    15ml of 0.5% bottle

  • Levobunolol HCl
    5ml of 0.5% bottle

How to take Levobunolol

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

  • Ophthalmic routeShake the eye drops well just before each use.

  • Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Ophthalmic routeTo use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

  • If you wear contact lenses, remove them before using this medicine. You may insert them again after 15 minutes.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Ophthalmic routeLie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • If you wear contact lenses, remove them before using this medicine. You may insert them again after 15 minutes.

  • Ophthalmic routeTo use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Ophthalmic routeWash your hands with soap and water before and after using this medicine.

  • Ophthalmic routeShake the eye drops well just before each use.

What to do if you miss a dose of Levobunolol

  • Do not put in two doses at the same time.

  • If you use the eye drops once a day, apply as soon as possible. If not remembered till next day, apply only once that day.

  • If you use the eye drops more than once a day, apply as soon as possible unless it is close to the time for the next dose. If almost time for the next dose, skip the missed dose and go back to your regular schedule.

Levobunolol contraindications

  • This medicine is not right for everyone. Do not use if you had an allergic reaction to levobunolol, a similar medicine, or sulfites, or if you have asthma, severe COPD, heart failure, heart rhythm problems, slow heartbeat, or a history of asthma.

Levobunolol warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have heart disease, diabetes, an overactive thyroid, lung or breathing problems, blood vessel problems (including Raynaud phenomenon), myasthenia gravis, or a history of heart failure.

  • Ophthalmic routeIf you hurt your eye, develop an eye infection, or need to have eye surgery, talk with your doctor right away. You may need to change your medicine or stop using it.

  • Tell any doctor or dentist who treats you that you are using this medicine. You may need to stop using this medicine several days before you have surgery or medical tests.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Swelling of legs or ankles

  • Hallucinations

  • Fever or sore throat

Levobunolol interactions

  • Do not use this medicine if you are also using a beta-blocker medicine that is taken by the mouth.

  • Some medicines can affect how levobunolol works. Tell your doctor if you are using any of the following:Digitalis, reserpineBlood pressure medicineInsulin or other diabetes medicineMedicine to treat depression

  • Talk with your doctor before use if you are pregnant or breastfeeding.

Levobunolol side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Chest pain, trouble breathing

  • Muscle weakness

  • Severe eye irritation or inflammation

  • Slow, uneven heartbeat

  • Swelling in your hands, ankles, or feet

  • Fever or sore throat

  • Cold hands and feet

Less Serious Side Effects

  • Tingling or pain in your fingers or toes when exposed to cold temperature

  • Nervousness

  • Dizziness, drowsiness, or confusion

  • Nausea

  • Stinging or burning of the eye

  • Eye that is sensitive to light

  • Cold hands and feet

  • Problems having sex

  • Redness, itching or watery eye(s)

Subscribe to our savings newsletter

Health education, drug info, wellness & more

By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.