What is Lodosyn: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Lodosyn overview

BRAND NAMES:

  • Lodosyn, Lodosyn

Generic Names:

  • Carbidopa

Uses:

  • Treats symptoms of Parkinson disease.

Therapeutic Classes:

  • Antiparkinsonian

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Lodosyn used for?

Lodosyn is used to treat symptoms of Parkinson's disease such as shakiness, stiffness, difficulty moving. It works by changing into dopamine in the brain, helping to control movement.

What form(s) does Lodosyn come in

  • Tablet

What are common Lodosyn doses?

  • Tablet 25MG

Common Lodosyn prescriptions

  • Lodosyn
    25mg tablet

How to take Lodosyn

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • Take this medicine at the same time you take your levodopa or Sinemet®, as directed.

  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take this medicine at the same time you take your levodopa or Sinemet®, as directed.

  • Missed dose: You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

What to do if you miss a dose of Lodosyn

Lodosyn contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to carbidopa, or if you have narrow-angle glaucoma.

Lodosyn warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney, liver, or lung disease, a stomach ulcer, diabetes, thyroid problems, growth problems, heart disease, low blood pressure, or a history of heart attack, melanoma, or mental or emotional problems.

  • This medicine may cause the following problems: Increased risk for melanomaNeuroleptic malignant syndrome (NMS)Thoughts of hurting yourself, or suicidal thoughts

  • This medicine may make you dizzy or suddenly fall asleep. Do not drive or do anything that could be dangerous until you know how this medicine affects you.

  • Do not stop using this medicine suddenly. Your doctor will need to slowly decrease your dose before you stop it completely.

  • Tell any doctor or dentist who treats you that you are taking this medicine. This medicine may affect the results of certain medical tests, including tests often used by people who have diabetes.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • This medicine might cause your saliva, sweat, or urine to become dark red, brown, or black. This may stain clothing but is otherwise harmless.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Vision problems, such as double or blurred vision

Lodosyn interactions

  • Do not use carbidopa if you are using an MAO inhibitor or have used one within the past 14 days.

  • Some medicines and foods can affect how carbidopa works. Tell your doctor if you are taking any of the following: Blood pressure medicine, such as atenolol, hydrochlorothiazide (HCTZ), lisinopril, metoprololIsoniazidMetoclopramidePapaverinePhenothiazine medicine, such as promethazine, chlorpromazine PhenytoinRisperidoneTricyclic antidepressant medicineVitamin supplements that contain iron

  • Tell your doctor if you use anything else that makes you sleepy. Some examples are allergy medicine, narcotic pain medicine, and alcohol.

  • Do not eat high-protein foods while you are taking carbidopa.

  • Tell any doctor or dentist who treats you that you are taking this medicine. This medicine may affect the results of certain medical tests, including tests often used by people who have diabetes.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • This medicine might cause your saliva, sweat, or urine to become dark red, brown, or black. This may stain clothing but is otherwise harmless.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Lodosyn side effects

Serious Side Effects

  • High fever, severe muscle pain or stiffness, or confusion

  • Severe anxiety or agitation

  • Vision problems, such as double or blurred vision

  • Lightheadedness, fainting, or fast heartbeat

  • Repetitive movements you cannot control (either new or worse than usual)

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Change in how much or how often you urinate

  • Depression, or thoughts of hurting yourself

  • Hallucinations (seeing or hearing things that are not truly there)

Less Serious Side Effects

  • Warmth or redness in your face, neck, arms, or upper chest

  • Dry mouth, loss of appetite

  • Mild nausea, vomiting, diarrhea, constipation, or stomach pain

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