What is Lorbrena: Uses, Warnings & Interactions

How to take Lorbrena

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• Swallow the tablet whole. Do not chew, crush, or split it.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Missed dose: If you miss a dose and it is within 4 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take extra medicine to make up for a missed dose. Do not take extra medicine if you vomit.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• Swallow the tablet whole. Do not chew, crush, or split it.

• Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

• Missed dose: If you miss a dose and it is within 4 hours of your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take extra medicine to make up for a missed dose. Do not take extra medicine if you vomit.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Lorbrena

Lorbrena contraindications

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to lorlatinib, or if you are pregnant.

Lorbrena warnings

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Oral routeCancer medicine can cause nausea or vomiting, sometimes even after you receive medicine to prevent these effects. Ask your doctor or nurse about other ways to control any nausea or vomiting that might happen.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Oral routeThis medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. If you are a woman who can bear children, your doctor may give you a pregnancy test before you start using this medicine to make sure you are not pregnant. Women should use an effective form of birth control (including condoms or spermicide along with your pills) to keep from getting pregnant during treatment with this medicine and for at least 6 months after the last dose. Men should also use an effective form of birth control during treatment with this medicine and for at least 3 months after the last dose.

• Do not breastfeed while you are using this medicine and for 7 days after the last dose.

• Tell your doctor if you have kidney disease, liver disease, lung or breathing problems, heart rhythm problems, or a history of depression or seizures.

• This medicine may cause the following problems:Liver problems, when used with other medicinesBrain or nerve problems, including seizuresChanges in mood or behavior, including thoughts of suicideHigh cholesterol or fat in the bloodHeart rhythm problems, including heart blockInterstitial lung disease or pneumonitis, which may be life-threatening

• This medicine could cause infertility in some men. Talk with your doctor before using this medicine if you plan to have children.

• Oral routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

Lorbrena interactions

• Some medicines can affect how lorlatinib works. Tell your doctor if you are using acetaminophen, bupropion, fexofenadine, itraconazole, midazolam, St John's wort, tolbutamide, or birth control pills.

• Do not use this medicine together with rifampin.