Makena
Hydroxyprogesterone Caproate
Lowers the risk of delivering your baby too early (preterm birth).
Endocrine-Metabolic Agent
Injectable
By injection
Injectable
Vial 1ML of 250MG/ML
Vial 5ML of 250MG/ML
Syringe 1.1000000238418579ML of 275MG/1.1ML
Makena
1.1ml of 275mg/1.1ml syringe
Makena
1ml of 250mg/ml vial
Makena
5ml of 250mg/ml vial
Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into a muscle or under your skin.
Injection routeA nurse or other health provider will give you this medicine.
This medicine is usually given every 7 days. You will begin receiving this medicine between weeks 16 and 20 of your pregnancy.
You will continue to receive this medicine once a week until week 37 of your pregnancy or until you give birth.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Missed dose:Oral routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions.
You will continue to receive this medicine once a week until week 37 of your pregnancy or until you give birth.
This medicine is usually given every 7 days. You will begin receiving this medicine between weeks 16 and 20 of your pregnancy.
Missed dose:Oral routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor for instructions.
Injection routeA nurse or other health provider will give you this medicine.
Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.
Your doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot into a muscle or under your skin.
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hydroxyprogesterone or castor oil, or if you have active liver disease or liver cancer, high blood pressure that is not controlled, unusual vaginal bleeding that has not been checked by a doctor, jaundice (yellow skin or eyes) caused by pregnancy, or a history of breast cancer or blood clots.
Tell your doctor if you are breastfeeding, or if you have kidney problems, heart problems, asthma, diabetes, high blood pressure, migraines, epilepsy, or a history of seizures or depression.
This medicine may cause blood clots and high blood pressure.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Numbness or weakness in one side of your body, sudden or severe headache, problems with vision, speech, or walking
Rapid weight gain, swelling in your hands, ankle, or feet
Yellow skin or eyes
Tell your doctor if you are breastfeeding, or if you have asthma, diabetes, high blood pressure, migraines, kidney problems, heart problems, or a history of seizures, depression or cancer.
This medicine may cause blood clots.
Serious Side Effects
Chest pain, trouble breathing, coughing up blood
Yellow skin or eyes
Rapid weight gain, swelling in your hands, ankle, or feet
Pain in your lower leg (calf)
Changes in mood or behavior
Numbness or weakness in one side of your body, sudden or severe headache, problems with vision, speech, or walking
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Less Serious Side Effects
Pain, itching, swelling, or a lump under your skin where the shot is given
Health education, drug info, wellness & more
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2025 SingleCare Administrators. All rights reserved
© 2025 SingleCare Administrators. All rights reserved