Learn more about misoprostol
Misoprostol is a generic prescription drug used to prevent stomach ulcers in patients who are taking NSAIDs (non-steroidal anti-inflammatory drugs) like aspirin. It is also prescribed for other patients at high risk of developing stomach ulcers, such as those with a history of stomach ulcers. Misoprostol is used off-label—that is, a use not approved by the FDA—to induce labor, treat post-partum bleeding, induce miscarriage when the fetus has died, or terminate a pregnancy within the first three months of gestation. Misoprostol is nearly identical to hormones in the body called prostaglandins, which help reduce stomach acid production and protect the lining of the stomach. Prostaglandins also play a role in wound healing, bleeding, clotting, and uterine contractions.
The average retail cost of Misoprostol is normally $20.10 for 4, 200mcg tablets of Misoprostol. A SingleCare Misoprostol coupon may reduce that price to $5.99 for 4, 200mcg tablets of generic Misoprostol.
Edit your dosage
Get alerted when the price
changes more than 10%
changes more than 10%
1 tablet, 100mcgEdit
$8.99
$ 5.99
$3 off with signupwith signup
Show this free card to your pharmacist.
$8.99
$ 5.99
$3 off with signupwith signup
$10.97
$ 7.97
$3 off with signupwith signup
$10.97
$ 7.97
$3 off with signupwith signup
$13.85
$ 10.85
$3 off with signupwith signup
$ 11.59
$ 11.60
$ 13.84
$19.81
$ 16.81
$3 off with signupwith signup
About SingleCare Pricing
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 12/05/2025
Members save the most
Save big on your prescriptions
with the free SingleCare app.
4.8 average ratingText a link to get the app
About Misoprostol
Misoprostol is a generic prescription drug used to prevent stomach ulcers in patients who are taking NSAIDs (non-steroidal anti-inflammatory drugs) like aspirin. It is also prescribed for other patients at high risk of developing stomach ulcers, such as those with a history of stomach ulcers. Misoprostol is used off-label—that is, a use not approved by the FDA—to induce labor, treat post-partum bleeding, induce miscarriage when the fetus has died, or terminate a pregnancy within the first three months of gestation. Misoprostol is nearly identical to hormones in the body called prostaglandins, which help reduce stomach acid production and protect the lining of the stomach. Prostaglandins also play a role in wound healing, bleeding, clotting, and uterine contractions.
The average retail cost of Misoprostol is normally $20.10 for 4, 200mcg tablets of Misoprostol. A SingleCare Misoprostol coupon may reduce that price to $5.99 for 4, 200mcg tablets of generic Misoprostol.
Learn more about misoprostol
Misoprostol Price History & Information
Price History for Misoprostol (Generic) & Cytotec (Brand)
4 count, tablet, 200mcgOur price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
Average 1-Month Prices for Misoprostol (Generic) & Cytotec (Brand)
4 count, tablet, 200mcg| Pharmacy | Misoprostol Retail Price | Misoprostol SingleCare Price |
|---|---|---|
| CVS Pharmacy | $29.96 | $26.72 |
| Walmart | $12.88 | $12.88 |
| Walgreens | $20.54 | $14.54 |
| Kroger Pharmacy | $20.53 | $13.10 |
| Albertsons Pharmacy | $29.36 | $22.24 |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
About Misoprostol
Misoprostol is a generic prescription drug used to prevent stomach ulcers in patients who are taking NSAIDs (non-steroidal anti-inflammatory drugs) like aspirin. It is also prescribed for other patients at high risk of developing stomach ulcers, such as those with a history of stomach ulcers. Misoprostol is used off-label—that is, a use not approved by the FDA—to induce labor, treat post-partum bleeding, induce miscarriage when the fetus has died, or terminate a pregnancy within the first three months of gestation. Misoprostol is nearly identical to hormones in the body called prostaglandins, which help reduce stomach acid production and protect the lining of the stomach. Prostaglandins also play a role in wound healing, bleeding, clotting, and uterine contractions.
The average retail cost of Misoprostol is normally $20.10 for 4, 200mcg tablets of Misoprostol. A SingleCare Misoprostol coupon may reduce that price to $5.99 for 4, 200mcg tablets of generic Misoprostol.
Misoprostol FAQs
How much does Misoprostol cost without insurance?
The retail price of Misoprostol without insurance averages $20.10 for 4, 200mcg tablets of Misoprostol. You could end up paying only $5.99 for 4, 200mcg tablets of generic Misoprostol using a SingleCare discount card. Save up to 80% off the retail price on many of your prescription drug needs with SingleCare.
How much does Misoprostol cost with insurance?
Misoprostol may be covered by some insurance plans. The copay of Misoprostol may differ between insurance plans. The lowest price of Misoprostol with SingleCare is $5.99 for 4, 200mcg tablets of generic Misoprostol. Ask your pharmacist to help you compare your insurance copay to the price with a SingleCare discount. Your Misoprostol price with SingleCare could be lower than the cost with insurance.
Does Medicare cover Misoprostol and how much does it cost?
Most Medicare Part D and Medicare Advantage prescription drug insurance plans cover generic Misoprostol. Thebrand-name version, Cytotec, is not typically covered. For patients without Medicare, SingleCare's free Misoprostol coupon may help reduce the cost of Misoprostol to $5.99 for 4, 200mcg tablets of generic Misoprostol. Search the SingleCare website or app for the price of both Misoprostol and its brand-name version for more information and possible savings.
Is there a generic of Misoprostol?
Misoprostol is a generic prescription drug manufactured by Novel Labs, Inc. It is also the active ingredient in brand-name Cytotec. A SingleCare prescription discount card may save you money on generic Misoprostol or Cytotec at local pharmacies near you, such as CVS or Duane Reade. Search the SingleCare website or app to find out more information about Misoprostol or Cytotec.
What is Misoprostol?
Misoprostol is a generic prescription drug used to prevent stomach ulcers in patients at high risk for developing stomach ulcers, such as those who may be taking NSAIDs (non-steroidal anti-inflammatory drugs), like aspirin or diclofenac. Misoprostol is used off-label to induce labor, treat post-partum bleeding, induce miscarriage when the fetus has died, or help terminate a pregnancy within the first three months of gestation.
Misoprostol is a prostaglandin analogue, which means that it is chemically similar to the natural prostaglandins found in the body. Misoprostol can help reduce stomach acid production and protect the mucosal lining of the stomach's gastrointestinal tract.
When taken orally, Misoprostol inhibits stomach acid production, reducing the risk of stomach ulcers for patients taking NSAID medication.
Misoprostol can soften the cervix and causes uterine contractions, so it is sometimes used off-label to induce labor. Misoprostol can induce contractions and bleeding to terminate a pregnancy in the first three months of gestation. Misoprostol can be used to soften the cervix in second-trimester surgical abortions. It can be used alone, but it is more effective when used in combination with mifepristone or methotrexate. Misoprostol is also used to prevent or treat postpartum bleeding.
Misoprostol is taken as an oral tablet. When used to terminate a pregnancy or induce labor, Misoprostol tablets must fully dissolve in the mouth next to the cheeks so that the drug directly enters the bloodstream.
What are the side effects of Misoprostol?
The side effects of Misoprostol include, but are not limited to, nausea, vomiting, diarrhea, constipation, headache, menstrual cramps, stomach cramps, and increased menstruation. Consult your healthcare provider for medical advice on other possible side effects associated with Misoprostol.
Most side effects of Misoprostol are mild and go away on their own after a few days. Tell your healthcare professional if you experience severe diarrhea, nausea, or abdominal cramping or persistent side effects that last more than eight days.
Allergic reactions are possible. Signs of an allergic reaction may include hives, trouble breathing, or facial swelling. Contact your doctor if you suspect you're having an allergic reaction to Misoprostol.
Do not take Misoprostol to reduce the risk of ulcers from NSAIDs if you are pregnant. Only use Misoprostol as prescribed by your healthcare professional.
Where are Misoprostol coupons from SingleCare accepted?
SingleCare is accepted at most national pharmacies and grocers, including the following:
Subscribe to our savings newsletter
Health education, drug info, wellness & more
By clicking 'Subscribe', I agree to SingleCare's Terms & Conditions.
