What is Mvasi: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 31, 2020

Mvasi overview

BRAND NAMES:

  • Mvasi, Zirabev, Avastin, Mvasi

Generic Names:

  • Mvasi

Uses:

  • Treats cancer, including colorectal, lung, glioblastoma, kidney, and cervical cancer., Treats cancer, including colorectal, lung, glioblastoma, kidney, liver, cervical, ovarian, fallopian tube, or primary peritoneal cancer.

Therapeutic Classes:

  • Immunological Agent, Antineoplastic Agent, Antineoplastic Agent

Forms:

  • Injectable, Injectable

How it’s taken:

  • By injection, By injection

What is Mvasi used for?

What form(s) does Mvasi come in

  • Injectable

  • Injectable

What are common Mvasi doses?

  • Vial 16ML of 400MG/16ML

Common Mvasi prescriptions

  • Mvasi
    16ml of 400mg/16ml vial

  • Mvasi
    4ml of 100mg/4ml vial

How to take Mvasi

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle will have to stay in place for 30 to 90 minutes every 2 or 3 weeks.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle will have to stay in place for 30 to 90 minutes every 2 or 3 weeks.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle will have to stay in place for at least 30 to 90 minutes.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Injection routeYou will receive this medicine while you are in a hospital or cancer treatment center. A nurse or other trained health professional will give you this medicine.

  • Missed dose: Injection routeThis medicine needs to be given on a fixed schedule. If you miss a dose, call your doctor, home health caregiver, or treatment clinic for instructions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. It must be given slowly, so the needle will have to stay in place for at least 30 to 90 minutes.

What to do if you miss a dose of Mvasi

Mvasi contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to bevacizumab.

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to bevacizumab, or if you are pregnant or breastfeeding.

Mvasi warnings

  • Injection routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control to prevent pregnancy while you are receiving this medicine and for at least 6 months after your last dose.

  • Do not breastfeed during treatment with this medicine and for at least 6 months after the last dose.

  • Tell your doctor if you have liver disease, kidney disease, high blood pressure, diabetes, heart disease, heart failure, bleeding problems, bowel blockage, or a history of heart attack, stroke, or blood clots. Tell your doctor if you had a recent surgery.

  • This medicine may cause the following problems: Stomach or bowel perforation (hole or tear)Fistula (abnormal opening) formation in the stomach, bowel, or other parts of the bodyIncreased risk for bleeding problems, blood clots, heart attack, or strokeHigh blood pressurePosterior reversible encephalopathy syndrome (brain disease)Kidney problemsInfusion reaction

  • This medicine may affect the way your body heals. Tell any doctor who treats you that you are using this medicine. You may need to stop receiving it at least 28 days before or after having surgery and until the wound has healed enough.

  • This medicine may cause problems in the ovaries. Talk with your doctor if you plan to have children. Some women are not able to get pregnant after they have used this medicine.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Unusual bleeding, bruising, or weakness, nosebleeds

  • Vomiting blood or material that looks like coffee grounds

  • This medicine may cause problems in the ovaries. Talk with your doctor if you plan to have children. Some women are not able to get pregnant after they have used this medicine.

  • Tell your doctor if you have kidney disease, liver disease, heart disease, heart failure, high blood pressure, diabetes, bleeding problems, bowel blockage, or a history of coughing up blood, heart attack, stroke, or blood clots.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Injection routeIt is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control to prevent pregnancy while you are receiving this medicine and for at least 6 months after your last dose.

  • This medicine may cause the following problems: Stomach or bowel perforation (hole or tear), including fistula (abnormal opening) formation in the stomach, bowel, or other parts of the bodyIncreased risk for bleeding problems, blood clots, heart attack, or strokeHigh blood pressurePosterior reversible encephalopathy syndrome (brain disease)Kidney problemsInfusion reactionHeart failure, especially when used together with anthracycline cancer medicines

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • This medicine may affect the way your body heals. Tell any doctor who treats you that you are using this medicine. You may need to stop using it at least four weeks before and after surgery.

  • Do not breastfeed during treatment with this medicine and for 6 months after the last dose.

Mvasi interactions

  • Do not receive bevacizumab-awwb together with cancer medicines containing anthracycline if you have heart failure.

  • Do not receive bevacizumab together with cancer medicines containing anthracycline if you have heart failure.

  • Injection routeMedicines used to treat cancer are very strong and can have many side effects. Before receiving this medicine, make sure you understand all the risks and benefits. It is important for you to work closely with your doctor during your treatment.

  • Talk with your doctor if you plan to have children. Some women are not able to get pregnant after they have used this medicine. Call your doctor if you do not have a menstrual period for 3 months.

  • Tell your doctor if you are breastfeeding, or if you have high blood pressure, diabetes, heart disease, bleeding problems, or a history of heart attack, stroke, or blood clots.

  • This medicine may cause the following problems: Gastrointestinal perforation (hole in your digestive system)Increased risk for bleeding problems, blood clots, heart attack, or strokeHigh blood pressureNervous system damageInfusion reaction

  • This medicine may affect the way your body heals. Tell any doctor who treats you that you are using this medicine. You may need to stop using it several weeks before and after surgery.

  • This medicine may make you bleed, bruise, or get infections more easily. Take precautions to prevent illness and injury. Wash your hands often.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Mvasi side effects

Serious Side Effects

  • Chest pain, coughing up blood, sudden or severe headache, problems with vision, speech, or walking, pain in your calf

  • Trouble swallowing, coughing or choking while you eat, cold sweat, bluish-colored skin

  • Numbness or weakness in your arm or leg, or on one side of your body

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Seizures, confusion, unusual drowsiness

  • Unusual bleeding, bruising, or weakness, nosebleeds

  • Vomiting blood or material that looks like coffee grounds

  • Constipation, stomach pain, nausea, vomiting

  • Bleeding from your rectum, black, tarry stools

  • Swelling in your hands, ankles, or feet

  • Bloody or cloudy urine, change in how much or how often you urinate

  • Fever, chills, trouble breathing, fainting, chest pain within a few hours after you receive this medicine

  • Numbness or weakness in your arm or leg, or on one side of your body

  • Trouble breathing or swallowing, coughing or choking while you eat, cold sweat, bluish-colored skin

  • Unusual bleeding, bruising, or weakness, nosebleeds

  • Chest pain, coughing up blood, sudden or severe headache, problems with vision, speech, or walking, pain in your calf

  • Blurred vision, dizziness, nervousness, pounding in the ears, slow or fast heartbeat

  • Seizures, confusion, unusual drowsiness

  • Constipation, stomach pain, nausea, vomiting

  • Fever, chills, trouble breathing, fainting, chest pain within a few hours after you receive this medicine

  • Swelling in your hands, ankles, or feet

  • Change in how much or how often you urinate, lower back or side pain, cloudy urine

  • Vomiting blood or material that looks like coffee grounds

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Bleeding from your rectum, black, tarry stools

Less Serious Side Effects

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Diarrhea, loss of appetite, stomach upset, change in sense of taste

  • Dry eyes or skin, redness, swelling, or scaly skin

  • Tiredness

  • Stuffy or runny nose

  • Loss of appetite, change in sense of taste

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Decreased weight

  • Tiredness

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