What is Naratriptan: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Naratriptan overview

BRAND NAMES:

  • Amerge

Generic Names:

  • Naratriptan Hcl

Uses:

  • Treats migraine headaches.

Therapeutic Classes:

  • Antimigraine

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Naratriptan used for?

What form(s) does Naratriptan come in

  • Tablet

What are common Naratriptan doses?

  • Box 9 Tablets

  • Tablet 1MG

  • Tablet 2.5MG

Common Naratriptan prescriptions

  • Naratriptan HCl
    9 tablets box

  • Naratriptan HCl
    1mg tablet

  • Naratriptan HCl
    2.5mg tablet

How to take Naratriptan

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Swallow the tablet with water or other liquid.

  • If your headache comes back or you do not get complete relief, wait at least 4 hours before you take another dose. Do not take more than 5 milligrams (mg) in 24 hours.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Use naratriptan only when you have a migraine. This medicine is not used on a regular schedule.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Swallow the tablet with water or other liquid.

  • Use naratriptan only when you have a migraine. This medicine is not used on a regular schedule.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • If your headache comes back or you do not get complete relief, wait at least 4 hours before you take another dose. Do not take more than 5 milligrams (mg) in 24 hours.

What to do if you miss a dose of Naratriptan

Naratriptan contraindications

  • This medicine is not right for everyone. Do not use if you had an allergic reaction to naratriptan, or if you have severe kidney or liver disease. Tell your doctor if you have heart or blood vessel problems, such as a history of heart attack or stroke, or if you have heart rhythm problems.

Naratriptan warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, high blood pressure, angina, diabetes, bowel disease, or a family history of heart disease. Tell your doctor if you have a history of blood circulation problems or if you smoke.

  • This medicine should be used only for classic or common migraine headaches. Do not use for any other kind of headache or pain.

  • This medicine may cause the following problems:Higher risk for abnormal heart rhythm, heart attack, angina, or strokeTightness or discomfort in your chest, neck, or jawSpasms in the blood vessels, such as Raynaud syndromeSerotonin syndrome

  • Your headaches may become worse if you use headache medicine for 10 or more days per month.

  • This medicine may make you dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Tightness or discomfort in your chest, neck, or jaw

  • Vision changes that are not part of a usual migraine

Naratriptan interactions

  • Do not use this medicine if you have taken another migraine headache medicine in the past 24 hours, such as another triptan or an ergot medicine.

  • Some foods and medicines can affect how naratriptan works. Tell your doctor if you are using medicine for depression or an MAO inhibitor.

  • This medicine may cause the following problems:Higher risk for abnormal heart rhythm, heart attack, angina, or strokeTightness or discomfort in your chest, neck, or jawSpasms in the blood vessels, such as Raynaud syndromeSerotonin syndrome

  • Your headaches may become worse if you use headache medicine for 10 or more days per month.

  • This medicine may make you dizzy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

  • Call your doctor if your symptoms do not improve or if they get worse.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Naratriptan side effects

Serious Side Effects

  • Anxiety, restlessness, fever, sweating, muscle spasms, twitching, diarrhea, seeing or hearing things that are not there

  • Numbness or tingling in your hands, arms, legs, or feet, color changes in your fingers or toes

  • Tightness or discomfort in your chest, neck, or jaw

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Sudden severe headache (other than the one being treated)

  • Fast, pounding, or uneven heartbeat

  • Chest pain, especially if it spreads to your arms, jaw, back, or neck

  • Severe stomach pain, bloody diarrhea, nausea, or vomiting

  • Vision changes that are not part of a usual migraine

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