What is Neo-Polycin: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Neo-Polycin overview

BRAND NAMES:

  • AK-Poly-Bac, Neo-Polycin, Neosporin, Polycin, Polytrim, Triple Antibiotic, Triple Antibiotic

Generic Names:

  • Neomycin-Bacitracin Zn-Polymyx

Uses:

  • Treats eye infections and swelling. Contains an antibiotic medicine and may sometimes contain a corticosteroid.

Therapeutic Classes:

  • Antibiotic, Antibiotic Combination

Forms:

  • Ointment, Liquid, Drop

How it’s taken:

  • Into the eye

What is Neo-Polycin used for?

What form(s) does Neo-Polycin come in

  • Ointment

  • Liquid

  • Drop

What are common Neo-Polycin doses?

  • Tube 3.5GM of 3.5-400-10000

Common Neo-Polycin prescriptions

  • Neo-Polycin
    3.5gm of 3.5-400-10000 tube

How to take Neo-Polycin

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine is not for long-term use.

  • Wash your hands before and after using the medicine.

  • Shake the eye drops well just before each use.

  • Lie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • To use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

  • To use the ointment:Hold the tip of the tube close to your eye with the other hand. Avoid touching the tip of the tube to your eye or finger. Squeeze a ribbon of ointment into the pocket between your lower lid and eyeball. Close your eyes for 1 to 2 minutes. Wipe the tip with a clean tissue and close the tube tightly. Keep the tube tightly closed when you are not using it.

  • Lie down or tilt your head back. With your index finger, pull down the lower lid of your eye to form a pocket.

  • Your doctor will tell you how much of this medicine to use and how often. Do not use more medicine or use it more often than your doctor tells you to. This medicine is not for long-term use.

  • Wash your hands before and after using the medicine.

  • Shake the eye drops well just before each use.

  • To use the ointment:Hold the tip of the tube close to your eye with the other hand. Avoid touching the tip of the tube to your eye or finger. Squeeze a ribbon of ointment into the pocket between your lower lid and eyeball. Close your eyes for 1 to 2 minutes. Wipe the tip with a clean tissue and close the tube tightly. Keep the tube tightly closed when you are not using it.

  • To use the eye drops: Hold the dropper close to your eye with the other hand. Drop the correct number of drops into the pocket made between your lower lid and eyeball. Gently close your eyes. Place your index finger over the inner corner of your eye for 1 minute. Do not rinse or wipe the dropper or allow it to touch anything, including your eye. Put the cap on the bottle right away. Keep the bottle upright when you are not using it.

What to do if you miss a dose of Neo-Polycin

  • If you miss a dose or forget to use your medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose.

  • Do not use extra medicine to make up for a missed dose.

Neo-Polycin contraindications

  • You should not use this medicine if you have had an allergic reaction to certain antibiotics. Make sure your doctor knows about all medicines you are allergic to, especially polymyxin B, gramicidin, neomycin, bacitracin, oxytertracycline, Neosporin®, Neocidin®, or Polysporin®.

Neo-Polycin warnings

  • If you are pregnant or breastfeeding, talk to your doctor before using this medicine.

  • Make sure your doctor knows if you have kidney problems.

  • If your condition does not get better, or gets worse, while you are using this medicine, call your doctor.

Neo-Polycin interactions

  • Talk to your doctor or pharmacist before using any other medicine or drops in your eyes.

  • Make sure your doctor knows if you have kidney problems.

  • If your condition does not get better, or gets worse, while you are using this medicine, call your doctor.

Neo-Polycin side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Severe eye itching, swelling, or redness

Less Serious Side Effects

  • Eye irritiation when the drops are put in

  • Watery eyes

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