What is Odomzo: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Apr 28, 2021

Odomzo overview

BRAND NAMES:

  • Odomzo

Generic Names:

  • Odomzo

Uses:

  • Treats basal cell carcinoma (skin cancer).

Therapeutic Classes:

  • Antineoplastic Agent

Forms:

  • Capsule

How it’s taken:

  • By mouth

What is Odomzo used for?

Odomzo is indicated for the treatment of adults with a form of skin cancer known as basal cell carcinoma that has spread to other parts of the body and cannot be treated with surgery or radiation. Odomzo stops the growth and spread of cancer cells in the body. It is available as a capsule.

What form(s) does Odomzo come in

  • Capsule

What are common Odomzo doses?

  • Capsule 200MG

Common Odomzo prescriptions

  • Odomzo
    200mg capsule

How to take Odomzo

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Take this medicine on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow the capsule whole.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Skip the missed dose and go back to your regular dosing schedule. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Odomzo

Odomzo contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to sonidegib, or if you are pregnant.

Odomzo warnings

  • This medicine may cause birth defects if either partner is using it during conception or pregnancy. Tell your doctor right away if you or your partner becomes pregnant. Women should use an effective form of birth control during treatment and for at least 20 months after the last dose. Men should use a condom during sex while they are taking this medicine and for at least 8 months after the last dose, even if they had a vasectomy.

  • Women should not breastfeed during treatment and for 20 months after the last dose.

  • This medicine may cause serious muscle problems that can lead to kidney damage.

  • Do not donate blood or blood products while you are taking this medicine and for 20 months after treatment ends. Men should not donate semen while taking this medicine and for 8 months after the last dose.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Odomzo interactions

  • Some medicines can affect how sonidegib works. Tell your doctor if you are using any of the following: Atazanavir, carbamazepine, diltiazem, efavirenz, fluconazole, itraconazole, ketoconazole, modafinil, nefazodone, phenobarbital, phenytoin, posaconazole, rifabutin, rifampin, saquinavir, St John's wort, telithromycin, voriconazole

  • Women should not breastfeed during treatment and for 20 months after the last dose.

  • This medicine may cause serious muscle problems that can lead to kidney damage.

  • Do not donate blood or blood products while you are taking this medicine and for 20 months after treatment ends. Men should not donate semen while taking this medicine and for 8 months after the last dose.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Odomzo side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Decrease in how much you urinate, dark urine

  • Muscle pain, tenderness, or weakness, muscle spasms

  • Hair loss

  • Tiredness

Less Serious Side Effects

  • Hair loss

  • Diarrhea, nausea

  • Change in or loss of sense of taste

  • Decreased appetite, weight loss

  • Tiredness

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