What is Orthovisc: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Jan 25, 2023

Orthovisc overview

BRAND NAMES:

  • TriVisc, Visco-3, TriLURON, Supartz FX, Orthovisc, Sodium Hyaluronate, Durolane, Euflexxa, Gel-One, GelSyn-3, GenVisc 850, Hyalgan, Hymovis, Monovisc

Generic Names:

  • Orthovisc

Uses:

  • Treats severe pain in your knee due to osteoarthritis.

Therapeutic Classes:

  • Musculoskeletal Agent, Antirheumatic, Cartilaginous Defect Repair Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Orthovisc used for?

Orthovisc is prescribed to patients with osteoarthritis. Orthovisc works by relieving inflammation in the knee by lubricating the joint to avoid pain.

What form(s) does Orthovisc come in

  • Injectable

What are common Orthovisc doses?

  • Syringe 2ml of 30mg/2ml

Common Orthovisc prescriptions

  • OrthoVisc
    2ml of 30mg/2ml syringe

How to take Orthovisc

  • Your doctor will tell you how many injections you will need. This medicine is injected into your knee joint.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Orthovisc

Orthovisc contraindications

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hyaluronic acid or if you have a bleeding disorder.

Orthovisc warnings

  • Tell your doctor if you are pregnant or breastfeeding, or if you have any allergies, including to birds, feathers, or eggs.

  • Rest your knee for 48 hours after you receive an injection. Do not do strenuous, weightbearing activities, such as jogging or tennis. Avoid activities that keep you standing for longer than 1 hour.

Orthovisc interactions

  • Tell your doctor if you are pregnant or breastfeeding, or if you have any allergies, including to birds, feathers, or eggs.

  • Rest your knee for 48 hours after you receive an injection. Do not do strenuous, weightbearing activities, such as jogging or tennis. Avoid activities that keep you standing for longer than 1 hour.

Orthovisc side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Pain, redness, or swelling where the medicine is injected

Less Serious Side Effects

  • Pain, redness, or swelling where the medicine is injected

  • Mild increase in pain or swelling in your knee