What is Ponvory: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Sep 17, 2021

Ponvory overview

BRAND NAMES:

  • Ponvory, Ponvory Starter Pack

Generic Names:

  • Ponvory

Uses:

  • Treats relapsing forms of multiple sclerosis (MS).

Therapeutic Classes:

  • Immune Modulator

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Ponvory used for?

What form(s) does Ponvory come in

  • Tablet

What are common Ponvory doses?

  • Tablet 20MG

How to take Ponvory

  • Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

  • If you are using this medicine and have certain heart conditions, your doctor may want you to stay in the medical facility for at least 4 hours when you take the next dose.

  • Swallow the tablet whole. Do not split, crush, or chew it.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: If you miss 1, 2, or 3 doses in a row during the initial dose titration or the maintenance dose, take it as soon as you remember, then go back to your regular dosing schedule. If you miss a dose for 4 days in a row during the initial dose titration or the maintenance dose, you will need to restart the dose titration.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Ponvory

Ponvory contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to ponesimod, or if you have had a heart attack, stroke, unstable chest pain, or heart failure within the last 6 months, or if you have heart rhythm problems (including arrhythmia or heart block) without a pacemaker.

Ponvory warnings

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment with this medicine and for at least 1 week after the last dose.

  • Tell your doctor if you are breastfeeding, or if you have liver disease, diabetes, breathing problems (including asthma, COPD), high blood pressure, any type of infection (including chickenpox), a weak immune system, or a history of uveitis (eye swelling) or skin cancer.

  • This medicine may cause the following problems: Increased risk of infections, which may be life-threatening (including meningitis, herpes, progressive multifocal leukoencephalopathy), heart rhythm problemsLung or breathing problems, liver problems, high blood pressure, increased risk of skin cancer (including basal cell carcinoma, melanoma, squamous cell carcinoma), eye or vision problem, brain problems, including posterior reversible encephalopathy syndrome (PRES)

  • Symptoms of your MS may return and become worse after stopping treatment with this medicine. Do not stop using this medicine without checking first with your doctor.

  • This medicine lowers the number of white blood cells. This weakens your immune system, so you may get infections more easily. Wash your hands often. Avoid people who are sick.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Ponvory interactions

  • Do not use this medicine after treatment with alemtuzumab.

  • Some medicines can affect how ponesimod works. Tell your doctor if you are using of any of the following: Carbamazepine, digoxin, diltiazem, phenytoin, rifampin, verapamilBeta blockers, medicine for heart rhythm problems (including amiodarone, procainamide, quinidine, sotalol), medicine that may cause heart rhythm problems, medicine the weakens the immune system (including beta interferon, glatiramer acetate, cancer medicine, steroid medicine)

  • This medicine may interfere with vaccines. Ask your doctor before you get a flu shot or any other vaccines. Do not use this medicine 1 to 2 weeks before and for 1 month after receiving a vaccine.

Ponvory side effects

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blurred vision or other changes in vision

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Fainting, dizziness, lightheadedness

  • Fast, slow, pounding, or uneven heartbeat

  • Fever, chills, cough, runny or stuffy nose, sore throat, body aches, neck stiffness, sensitivity to light

  • Skin growths, patches, or sores on the skin that do not heal quickly

  • Sudden or severe headache, confusion, seizures

  • Trouble breathing, chest tightness

  • Unusual bleeding, bruising, or weakness

Less Serious Side Effects

  • Arm or leg pain

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