What is Prezcobix: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Dec 30, 2020

Prezcobix overview

BRAND NAMES:

  • Prezcobix

Generic Names:

  • Prezcobix

Uses:

  • Treats HIV infection. HIV causes AIDS. This medicine does not cure HIV or AIDS, but combinations of drugs may slow the progress of the disease.

Therapeutic Classes:

  • Antiretroviral Agent

Forms:

  • Tablet

How it’s taken:

  • By mouth

What is Prezcobix used for?

What form(s) does Prezcobix come in

  • Tablet

What are common Prezcobix doses?

  • Tablet 800-150MG

Common Prezcobix prescriptions

  • Prezcobix
    30 tablets bottle

  • Prezcobix
    800-150mg tablet

How to take Prezcobix

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Oral routeIt is best to take this medicine with food or milk.

  • Do not stop using this medicine without checking first with your doctor. If you stop the medicine even briefly, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

  • Do not stop using this medicine without checking first with your doctor. If you stop the medicine even briefly, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Oral routeIt is best to take this medicine with food or milk.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

What to do if you miss a dose of Prezcobix

Prezcobix contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to darunavir or cobicistat.

Prezcobix warnings

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Birth control pills may not work as well to prevent pregnancy when used with this medicine. Use another form of birth control (including condoms or spermicide) along with your pills.

  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.

  • Tell your doctor if you have kidney disease, liver disease, diabetes, hemophilia, or an allergy to sulfa drugs.

  • This medicine may cause the following problems:Liver problemsSerious skin reactionsNew or worsening kidney problemsHigh blood sugar levels, which could become permanentIncreased risk of bleeding

  • Your immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Prezcobix interactions

  • You must avoid many other medicines while you are using darunavir/cobicistat. These medicines used together could cause serious health problems, including death. Medicines you must avoid include the following: alfuzosin, carbamazepine, cisapride, dronedarone, elbasvir/grazoprevir, ivabradine, lomitapide, lovastatin, lurasidone, naloxegol, oral midazolam, phenobarbital, phenytoin, pimozide, ranolazine, rifampin, sildenafil for pulmonary hypertension, simvastatin, St John's wort, triazolam, and ergot medicines (including dihydroergotamine, ergotamine, or methylergonovine). Do not use this medicine together with colchicine if you have kidney or liver disease.

  • Tell your doctor if you are using any of the following:Birth control pill that contains drospirenone or ethinylestradiolMedicine to treat an infection (including clarithromycin, erythromycin, telithromycin)Medicine to treat mental illness (including quetiapine)Seizure medicine (including eslicarbazepine, oxcarbazepine)Steroid medicine (including betamethasone, budesonide, ciclesonide, dexamethasone, fluticasone, methylprednisolone, mometasone, triamcinolone) Your doctor may recommend you to use other similar medicines or may change your dose if you are using these medicines together with darunavir/cobicistat.

  • There are many other drugs that can affect how this medicine works. Ask your doctor before you use any other medicine.

  • If you also take didanosine, take it 1 hour before or 2 hours after you take this medicine.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Prezcobix side effects

Serious Side Effects

  • Rash with fever, tiredness, joint or muscle pain

  • Change in how much or how often you urinate, lower back or side pain

  • Dark urine or pale stools, nausea, vomiting, loss of appetite, stomach pain, yellow skin or eyes

  • Increased hunger or thirst, weight loss

  • Blistering, peeling, red skin rash

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Weight gain around your neck, upper back, breast, or waist, moon-shaped face