A Probiotic is an over-the-counter supplement or medication that provides live cultures of “good” bacteria or yeast that may have health benefits. Probiotics come in three types: Probiotics taken orally (dietary supplements) or rectally (suppositories or enemas) to colonize the gut with “good” microorganisms; vaginal suppositories to colonize the vagina with “good” bacteria; and topical Probiotics to colonize skin tissues or hair with “good” bacteria. Depending on the product and the ingredients, a variety of health benefit claims are made for Probiotics including contributing to intestinal, vaginal, or skin health, treating specific health conditions or diseases, preventing infections, increasing nutrient absorption, strengthening the immune system, stabilizing mood, lowering stress, or improving cognitive function. Probiotic dietary supplements are sometimes prescribed to patients after antibiotic therapy to help repopulate the gut with “good” microorganisms. Individual brands and products are priced differently, but the retail price of Probiotic products averages $41.59 for 60, 250mg capsules. With a SingleCare Probiotic coupon, the average price is $24.50. SingleCare discounts are eligible for over-the-counter products, like Probiotic, when prescribed by a physician.
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SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 05/05/2026
A Probiotic is an over-the-counter supplement or medication that provides live cultures of “good” bacteria or yeast that may have health benefits. Probiotics come in three types: Probiotics taken orally (dietary supplements) or rectally (suppositories or enemas) to colonize the gut with “good” microorganisms; vaginal suppositories to colonize the vagina with “good” bacteria; and topical Probiotics to colonize skin tissues or hair with “good” bacteria. Depending on the product and the ingredients, a variety of health benefit claims are made for Probiotics including contributing to intestinal, vaginal, or skin health, treating specific health conditions or diseases, preventing infections, increasing nutrient absorption, strengthening the immune system, stabilizing mood, lowering stress, or improving cognitive function. Probiotic dietary supplements are sometimes prescribed to patients after antibiotic therapy to help repopulate the gut with “good” microorganisms. Individual brands and products are priced differently, but the retail price of Probiotic products averages $41.59 for 60, 250mg capsules. With a SingleCare Probiotic coupon, the average price is $24.50. SingleCare discounts are eligible for over-the-counter products, like Probiotic, when prescribed by a physician.
Our price history metrics are calculated from aggregate prescription data that we receive from all participating pharmacies. This chart updates daily to show new price fluctuations. If a data point is missing from the chart, it is because we do not have enough data to produce a reliable figure.
| Pharmacy | Florastor Retail Price | Probiotic Retail Price | Probiotic SingleCare Price |
|---|---|---|---|
| Walmart | - | - | - |
| Walgreens | $72.48 | $37.20 | $19.20 |
| Kroger Pharmacy | $60.90 | $28.80 | $28.80 |
| Albertsons Pharmacy | - | - | - |
These prices are based on the last month of SingleCare prescription fill data by major pharmacy. This table updates daily to show the most accurate typical prices by pharmacies. If a data point is missing from the table, it is because we do not have enough data to produce a reliable figure.
A Probiotic is an over-the-counter supplement or medication that provides live cultures of “good” bacteria or yeast that may have health benefits. Probiotics come in three types: Probiotics taken orally (dietary supplements) or rectally (suppositories or enemas) to colonize the gut with “good” microorganisms; vaginal suppositories to colonize the vagina with “good” bacteria; and topical Probiotics to colonize skin tissues or hair with “good” bacteria. Depending on the product and the ingredients, a variety of health benefit claims are made for Probiotics including contributing to intestinal, vaginal, or skin health, treating specific health conditions or diseases, preventing infections, increasing nutrient absorption, strengthening the immune system, stabilizing mood, lowering stress, or improving cognitive function. Probiotic dietary supplements are sometimes prescribed to patients after antibiotic therapy to help repopulate the gut with “good” microorganisms. Individual brands and products are priced differently, but the retail price of Probiotic products averages $41.59 for 60, 250mg capsules. With a SingleCare Probiotic coupon, the average price is $24.50. SingleCare discounts are eligible for over-the-counter products, like Probiotic, when prescribed by a physician.
Probiotics are marketed as a broad variety of products under several premium and brand names. The average price of Probiotic is $41.59. With a SingleCare discount card and a prescription for Probiotic, you pay only $24.50 for 60, 250mg capsules.
Probiotics are neither prescription drugs nor covered by insurance plans. It is unlikely health insurance will pay for Probiotic even with a doctor's prescription. Currently, however, you will pay only $24.50 for 60, 250mg capsules of Probiotic with a SingleCare savings card.
Because Probiotics are over-the-counter products, Medicare prescription drug plans do not cover purchases them. For Medicare patients with a prescription for a Probiotic, bring your SingleCare discount card to any SingleCare participating pharmacy and pay as little as $24.50 for 60, 250mg capsules.
Probiotic is marketed as a wide variety of products under many premium and brand names. The best-known premium brands include Culturelle (DSM), Align (Proctor & Gamble), Florajen (Clarion Brands), Phillips Colon Health (Bayer), Florastor, TruBiotics (Bayer), and Purfem (vaginal suppository) (DSM). Generic probiotics are widely available as dietary supplements under familiar brand names such as CVS, Up & Up, Equate, and Jarrow. They contain some or all the bacteria strains found in premium brand products.
A Probiotic is an over-the-counter supplement or medication that provides live cultures of “good” bacteria or yeast that may have health benefits. Probiotics come in three types: Probiotics taken orally (dietary supplements) or rectally (suppositories or enemas) to colonize the gut with “good” microorganisms; vaginal suppositories to colonize the vagina with “good” bacteria; and topical Probiotics to colonize skin tissues or hair with “good” bacteria or yeast.
Dietary supplements are the most familiar form of Probiotic. They are intended to colonize the gut with “good” bacteria (Lactobacillus or Bifidobacterium) or “good” yeast (Saccharomyces). These microorganisms have been shown to improve digestion, the absorption of nutrients by the immune system, and prevent or reduce bacterial infections in the gut. Many Probiotic supplements are also marketed as strengthening the immune system, improving vaginal health, treating various illnesses, stabilizing mood, and enhancing cognition and memory, but these benefits have not been demonstrated. Probiotic supplements are often prescribed to patients after a course of antibiotics to help repopulate the gastrointestinal system with critical microorganisms.
Probiotics are also administered rectally either as suppositories or enemas to populate the colon with “good” bacteria to treat or prevent gastrointestinal infections and conditions.
Probiotic vaginal suppositories are intended to colonize the vagina with “good” bacteria (Lactobacillus). They have been shown to help treat or prevent bacterial (vaginosis) or yeast infections in the vagina. They are also marketed as reducing vaginal dryness, improving vaginal odor, strengthening the immune system, and stabilizing mood, but these claims have not been verified.
Probiotics are becoming a popular ingredient in skincare and hair products. They are intended to colonize the skin or scalp with “good” microorganisms (Lactobacillus, Bifidobacterium, and Streptococcus thermophilus for skin creams and Lactobacillus, Lactococcus, Saccharomyces, and Kluyveromyces in shampoos). These products are claimed to protect the skin from bacterial infections and swelling (“calming” skin creams), removing free radicals from skin tissues, and promoting the growth of healthy hair. Some “probiotic” skin creams and shampoos, however, use a substance (Bifida ferment lysate) that is derived from the fermentation of dead bifidobacteria, but these products do not contain live cultures of beneficial microorganisms.
Side effects of Probiotics will depend on the product and how it is used. Side effects of topical and vaginal Probiotics are minimal and rarely experienced. Common side effects of Probiotic supplements, rectal suppositories, and enemas include but are not limited to gas, bloating, constipation, and thirst, but these usually subside within a day. While not an allergic reaction, the body sometimes reacts to the live bacteria by releasing histamines to fight off what the body thinks is an infection. Histamines cause the symptoms of allergic reactions, such as swelling, itching, and discomfort.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2026 SingleCare Administrators. All rights reserved