What is Profilnine: Uses, Warnings & Interactions

Updated May 14, 2025  •  Published Oct 19, 2022

Profilnine overview

BRAND NAMES:

  • Profilnine, Profilnine SD

Generic Names:

  • Profilnine

Uses:

  • Prevents and controls bleeding in patients with hemophilia B (also known as Factor IX deficiency or Christmas disease).

Therapeutic Classes:

  • Hemostatic, Antihemophilic Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Profilnine used for?

Profilnine SD is a prescription only medication that is used by patients diagnosed with hemophilia B to manage or prevent bleeding episodes. Profilnine B is used to clot the blood within the body to treat or avoid a bleeding episode.

What form(s) does Profilnine come in

  • Injectable

What are common Profilnine doses?

  • Solution Reconstituted 500unit

  • Solution Reconstituted 1500unit

Common Profilnine prescriptions

  • Profilnine
    1000unit solution reconstituted

  • Profilnine
    1500unit solution reconstituted

  • Profilnine
    500unit solution reconstituted

How to take Profilnine

  • Take the medicine out of the refrigerator before you are ready to use it. This will let the medicine warm up to room temperature before use.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Injection routeUse a new needle and syringe each time you inject your medicine.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Profilnine

  • Injection routeCall your doctor or pharmacist for instructions.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Injection routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any leftover medicine, containers, and other supplies. Throw away old medicine after the expiration date has passed.

  • Injection routeIf you store this medicine at home, keep it in the refrigerator. Do not freeze.

Profilnine contraindications

  • You should not receive this medicine if you have had an allergic reaction to factor IX complex human.

Profilnine warnings

  • Make sure your doctor knows if you are pregnant or breast feeding.

  • Sudden severe headache, problems with vision, speech, or walking.

  • Severe nausea, joint pains, skin rash, yellowing of skin or whites of your eyes.

  • Pain in your lower leg (calf).

  • Numbness or weakness in your arm, leg, or one side of your body.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made of human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing during manufacture of these medicines. Although the risk is low, talk with your doctor if you have concerns.

  • Make sure your doctor knows if you have liver disease or if you have recently had surgery.

Profilnine interactions

  • Make sure your doctor knows if you have liver disease or if you have recently had surgery.

  • This medicine is made from donated human blood. Some human blood products have transmitted certain viruses to people who have received them. The risk of getting a virus from medicines made of human blood has been greatly reduced in recent years. This is the result of required testing of human donors for certain viruses, and testing during manufacture of these medicines. Although the risk is low, talk with your doctor if you have concerns.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Make sure your doctor knows if you are pregnant or breast feeding.

Profilnine side effects

Serious Side Effects

  • Numbness or weakness in your arm, leg, or one side of your body.

  • Sudden severe headache, problems with vision, speech, or walking.

  • Pain in your lower leg (calf).

  • Fever, chills.

  • Chest pain, trouble breathing, or coughing up blood.

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Lightheadedness or fainting.

  • Severe nausea, joint pains, skin rash, yellowing of skin or whites of your eyes.

Less Serious Side Effects

  • Nausea, or mild stomach pain.

  • Pain, itching, swelling, burning or a lump under your skin where the needle is placed.

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