What is Prolastin-C? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

Prolastin-C overview

BRAND NAMES:

  • Aralast NP, Glassia, Prolastin-C, Zemaira

Generic Names:

  • Prolastin-C

Uses:

  • Treats emphysema.

Therapeutic Classes:

  • Blood Modifier Agent

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Prolastin-C used for?

Zemaira is a prescription-only medication that works by increasing the plasma levels of patients with alpha 1-antitrypsin deficiency. Zemaira replaces the deficient plasma levels to help patients avoid lung or liver problems that are commonly associated with alpha 1-antitrypsin deficiency.

What form(s) does Prolastin-C come in?

  • Injectable

What are common Prolastin-C dosages?

  • Solution Reconstituted 1000MG

Prolastin-C images - What does Prolastin-C look like?

  • Prolastin-C
    1000mg/20ml solution

  • Prolastin-C
    1000mg solution reconstituted

How to take Prolastin-C

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • This medicine is usually given once a week on a regular schedule.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Record and keep a treatment infusion log. This includes information, including lot number, time, date, and any reactions.

  • Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.

  • This medicine is usually given once a week on a regular schedule.

  • Read and follow the patient instructions that come with this medicine. Talk to your doctor or pharmacist if you have any questions.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Record and keep a treatment infusion log. This includes information, including lot number, time, date, and any reactions.

  • Injection routeYou may be taught how to give your medicine at home. Make sure you understand all instructions before giving yourself an injection. Do not use more medicine or use it more often than your doctor tells you to.

What to do if you miss a dose of Prolastin-C

Prolastin-C contraindications - Who shouldn't take Prolastin-C?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to alpha-1 proteinase inhibitor.

Prolastin-C warnings

  • Tell your doctor if you are pregnant or breastfeeding.

  • This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns. Your doctor may give you a hepatitis B vaccine before you receive this medicine.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

  • Lightheadedness, dizziness, or fainting

  • Worsening of breathing problems

Prolastin-C interactions & what to avoid when taking Prolastin-C

  • Tell your doctor if you are pregnant or breastfeeding.

  • This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns. Your doctor may give you a hepatitis B vaccine before you receive this medicine.

  • Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

Prolastin-C side effects - How does Prolastin-C make you feel?

Serious Side Effects

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Change in how much or how often you urinate, painful or difficult urination

  • Chest tightness or discomfort

  • Lightheadedness, dizziness, or fainting

  • Worsening of breathing problems

Less Serious Side Effects

  • Pain, itching, burning, swelling, or a lump under your skin where the needle is placed

  • Warmth or redness in your face, neck, arms, or upper chest

  • Muscle or bone pain or discomfort

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