Rituxan is a brand-name prescription injection that treats a number of diseases involving B-lymphocytes, a type of white blood cell that produces antibodies. As an anti-cancer drug, Rituxan treats chronic lymphocytic leukemia and particular forms of non-Hodgkin's lymphomas. All are cancers of B-cell lymphocytes. Rituxan also treats active rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris, all autoimmune diseases that attack healthy tissues in the body. The active ingredient in Rituxan, rituximab, is an antibody that attaches to a protein on the surface of B-cell lymphocytes and signals the immune system to kill them. Rituxan cost is normally $13,417.79 at full price. A SingleCare Rituxan coupon reduces that price to $9,190.51. Ask the clinic or hospital where you receive your Rituxan infusion if they will accept a SingleCare Rituxan coupon.
Edit your dosage
1 vial, 10ml of 100mg/10mlEdit
You have 0.00 in available bonus savings. Bonus savings will be automatically applied to your next eligible prescription fill.
Show this free card to your pharmacist.
SingleCare’s prescription prices are based on multiple sources. The prices we publish are our best estimate, but we cannot guarantee that the price we display will exactly match the price you receive at the pharmacy. For an exact price, please contact your pharmacy and provide the BIN/GRP/PCN numbers shown on your SingleCare card.
Any SingleCare bonus savings, including the $3 signup bonus, may only be used once.
Prices updated: 04/12/2026
Rituxan is a brand-name prescription injection that treats a number of diseases involving B-lymphocytes, a type of white blood cell that produces antibodies. As an anti-cancer drug, Rituxan treats chronic lymphocytic leukemia and particular forms of non-Hodgkin's lymphomas. All are cancers of B-cell lymphocytes. Rituxan also treats active rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris, all autoimmune diseases that attack healthy tissues in the body. The active ingredient in Rituxan, rituximab, is an antibody that attaches to a protein on the surface of B-cell lymphocytes and signals the immune system to kill them. Rituxan cost is normally $13,417.79 at full price. A SingleCare Rituxan coupon reduces that price to $9,190.51. Ask the clinic or hospital where you receive your Rituxan infusion if they will accept a SingleCare Rituxan coupon.
Rituxan is a brand-name prescription injection that treats a number of diseases involving B-lymphocytes, a type of white blood cell that produces antibodies. As an anti-cancer drug, Rituxan treats chronic lymphocytic leukemia and particular forms of non-Hodgkin's lymphomas. All are cancers of B-cell lymphocytes. Rituxan also treats active rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris, all autoimmune diseases that attack healthy tissues in the body. The active ingredient in Rituxan, rituximab, is an antibody that attaches to a protein on the surface of B-cell lymphocytes and signals the immune system to kill them. Rituxan cost is normally $13,417.79 at full price. A SingleCare Rituxan coupon reduces that price to $9,190.51. Ask the clinic or hospital where you receive your Rituxan infusion if they will accept a SingleCare Rituxan coupon.
Rituxan costs around $13,417.79 for uninsured customers. With a SingleCare Rituxan coupon, you will pay $9,190.51 per 100, 50ML of 500MG/50ML Vial for the same prescription of Rituxan if the hospital or clinic where you receive Rituxan infusions will accept SingleCare.
Your copay for Rituxan will vary depending on your insurance plan and the price charged for Rituxan by the hospital or clinic where you get your infusion. However, Rituxan may be covered by your health insurance as a medical benefit rather than a prescription drug benefit. Ask the clinic or hospital where you receive Rituxan infusions if they will accept a SingleCare Rituxan coupon; you could pay $9,190.51.
Rituxan is usually not covered under Medicare prescription drug plans, but is covered under Medicare Part B as a medical benefit. Ask the clinic or hospital where you receive Rituxan infusions if they will accept a SingleCare Rituxan coupon; you could pay $9,190.51.
Rituxan is a brand-name prescription medicine with the active ingredient, rituximab. Generic rituximab is not available at this time. However, a biosimilar brand-name drug is available as Truxima.
Rituxan is a FDA-approved brand-name prescription drug administered as an intravenous injection that treats a number of diseases involving B-lymphocytes, a type of white blood cell that produces antibodies. As an anti-cancer drug, Rituxan treats chronic lymphocytic leukemia and particular forms of non-Hodgkin's lymphomas. Rituxan also treats active rheumatoid arthritis, granulomatosis with polyangiitis, microscopic polyangiitis, and pemphigus vulgaris, all autoimmune diseases that attack healthy tissues in the body.
Chronic lymphocytic leukemia and some types of non-Hodgkin's disease are cancers of B-cell lymphocytes. Cancerous B-cell lymphocytes grow uncontrollably. They are immature and defective and leave the patient vulnerable to infections.
Rheumatoid arthritis is a condition in which the immune system “misfires” and targets healthy joint tissue as if it were an infection. The immune system causes swelling, which damages the tissue and causes most of the symptoms of rheumatoid arthritis. Rituxan is always used in combination with steroids to treat rheumatoid arthritis to reduce the incidence and severity of infusion reactions.
Both granulomatosis with polyangiitis and microscopic polyangiitis are conditions where the immune system attacks blood vessels. The swelling closes off blood vessels, causing pain and potentially harming important organs such as the heart, liver, lungs, or nervous system.
Pemphigus vulgaris is a condition in which the immune system attacks proteins in the upper layers of the skin and mucous membranes. This causes blisters on the skin and in the mouth.
The active ingredient in Rituxan, rituximab, is an antibody that attaches to a protein on the surface of B-cell lymphocytes, called the CD20 antigen. Once attached, the antibody “paints a target” on the B-cell lymphocyte for other white blood cells to kill. This reduces cancerous B-cell lymphocytes for patients with B-cell cancers, but it also suppresses the immune system response in autoimmune diseases.
Rituxan is administered by a healthcare provider as an intravenous infusion. The infusion could last an hour or more. Each patient is premedicated with drugs to prevent infusion reactions and then closely monitored throughout the process for serious and potentially fatal allergic reactions. Rituxan is administered once weekly or biweekly for a total of anywhere from 4 to 12 doses depending on the underlying condition.
Common side effects of Rituxan include, but are not limited to, nausea, vomiting, diarrhea, indigestion, stomach pain, headache, fever, flushing, night sweats, muscle pain, joint pain, back pain, chest tightness, and dizziness.
Among the most serious side effects of Rituxan are severe and sometimes fatal infusion reactions. These are allergic reactions that could involve rash, dangerously low blood pressure, inability to breathe, respiratory failure, and heart attack. About 80% of infusion reactions happen during the first infusion. Patients will typically be given antihistamines and acetaminophen prior to infusion.
Rituxan can also cause a serious and sometimes fatal viral infection of the brain, multifocal leukoencephalopathy. Watch for symptoms such as memory problems, confusion, vision changes, problems with speech, problems walking, or weakness on one side of the body.
In cancer patients, Rituxan also may cause tumor lysis syndrome, a condition caused by the contents of dead cancer cells accumulating in the body. These cell contents radically change the balance of electrolytes in the body which can then lead to kidney problems and possible kidney failure. Symptoms are high blood potassium, low blood calcium, heart problems, and seizures.
Other severe side effects include heart problems, kidney problems, perforation of the bowels, and low white blood cell counts, making patients vulnerable to sometimes serious infections. Rituxan can reactivate hepatitis B infections, so patients will be screened for hepatitis B before receiving Rituxan. Talk to your healthcare professional about prescribing information, and if you experience any adverse reactions to Rituxan.
Kristi C. Torres, Pharm.D., is a 2005 graduate of The University of Texas at Austin. Her professional background includes academic teaching roles, district-level management for a nationwide pharmacy chain, and clinic-based pharmacy management. Dr. Torres has a wide range of experience in pharmacy operations and has traveled to many states to open and convert clinic-based pharmacies for one of the largest healthcare systems in the nation.
Currently, she works for Tarrytown Expocare Pharmacy in Austin, Texas, serving the intellectual and developmental disability community. There, she leads the order entry team, overseeing orders from across the country.
Dr. Torres began working in pharmacy at the age of 16 in a small East Texas town. She currently resides in Round Rock, Texas, with her daughter and a Shih-Tzu puppy.
...SingleCare is accepted at most national pharmacies and grocers, including the following:
Health education, drug info, wellness & more
SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
© 2026 SingleCare Administrators. All rights reserved
© 2026 SingleCare Administrators. All rights reserved