Saxenda is a brand-name weight management drug that works in much the same way as Ozempic. Both are GLP-1 agonists that decrease hunger feelings in the brain and slow stomach emptying. Saxenda is a daily injection administered with an injection pen. Each pen contains six doses at the recommended dosage. Saxenda can cause serious problems in people with pre-existing conditions like kidney disease or a family history of thyroid cancer, so it’s important to give the prescriber a complete medical history before starting Saxenda treatment.
Saxenda, Victoza
Liraglutide
Helps reduce body weight in adults and children 12 years of age and older who have an elevated body mass index (BMI)
Antidiabetic, glucagon-like peptide 1 (GLP-1) receptor agonist
Injectable
By injection
Healthcare professionals use Saxenda, along with diet and exercise, to reduce or control weight in adults and children 12 years of age and older. The FDA has approved its use only in people whose body mass index (BMI) exceeds 30 kg/m^2 or those with a BMI greater than 27 kg/m^2 who have another weight-related condition such as high cholesterol, high blood pressure, or Type 2 diabetes.
Injectable
6 mg/mL
For weight control: 3 mg injection once daily
Find more information about Saxenda dosage, forms, and strengths here.
Saxenda
18mg/3ml (6mg/ml) 3ml pen
Saxenda is a self-administered injection using a multi-dose injector pen.
Don’t use the injector pen until a healthcare provider has demonstrated how to use it.
You will be shown the body areas where this shot can be given. It is usually given in your stomach, thighs, or upper arms.
During the demonstration, ask the presenter about how to split doses between pens when there’s not enough medicine in one pen for a dose.
Read the Instructions for Use that come with this medicine before using the pen injector.
Take each dose exactly as instructed.
Do not use more medicine or administer injections more often than your healthcare provider tells you to.
Administer only one injection per day. The injection can be administered at any time during the day without regard to food.
Wash your hands before administering an injection.
Check the pen injector and the medicine inside the injector first. The pen should be undamaged and the medicine clear and colorless.
Always use a new NovoFine or NovoTwist needle. Push the needle onto the pen and twist it to tighten.
Select the correct dose using the dose selector. Do not use Saxenda injector pens if you can’t read the dose indicator.
Insert the needle into your skin.
You should be able to see the dose counter.
Press and hold down the dose button.
Continue pressing until the dose counter reads “0.”
Keep the needle in the skin for six seconds. If you remove it too soon, you may only get a partial dose.
Remove the needle.
If the dose button is pressed but the dose counter does not go to “0,” the needle may be blocked. You have not received your dose.
Change the needle.
Select the dose.
Inject the medicine.
Always remove the needle from the pen injector very carefully after each injection.
Dispose of the needle in a sharps container immediately.
Replace the cap on the Saxenda pen injector.
Never wash or soak the pen.
Store unused pen injectors in the refrigerator. Do not freeze.
Used pens can be stored at room temperature for up to 30 days.
Keep the pen injector away from heat and light.
Throw away the pen injector when:
It’s empty
The expiration date has passed
30 days have passed since you first started using it
If you miss a dose of this medicine, skip the missed dose and go back to your regular dosing schedule.
Never take extra medicine to make up for a missed dose.
If you miss a dose for three days or more, call the prescriber. You may need to restart the medicine at a lower dose.
This medicine is not right for everyone.
Do not use Saxenda if you:
Are pregnant
Have had an allergic reaction to liraglutide
Have a history or family history of multiple endocrine neoplasia syndrome type 2 (MEN 2) or medullary thyroid cancer (MTC)
Tell any doctor or other healthcare professional who treats you that you are taking Saxenda.
Before starting Saxenda, tell the prescriber if you are pregnant, planning to become pregnant, or breastfeeding.
The prescriber also needs to know about all other medical conditions you may have, particularly:
Kidney problems
Liver problems
Pancreas problems
Gallbladder disease
Stomach emptying problems
Problems digesting food
Depression, suicidal thoughts, and other mental health problems
Saxenda can cause serious medical problems, including:
Increased risk of thyroid cancer
Swelling of the pancreas
Kidney problems
Gallbladder disease
Rapid heartbeats
Low blood sugar (in people taking diabetes medications)
Suicidal thoughts and behaviors
The prescriber will need to perform regular checkups and lab tests to gauge the effectiveness of treatment and spot possible side effects. Keep all appointments.
To avoid potential drug interactions, tell the prescribing healthcare provider about all prescription drugs, over-the-counter medications, vitamins, and supplements you use, particularly:
Tell the prescriber if you are taking any other drugs orally. Tell all other healthcare professionals prescribing drugs that you are taking liraglutide injections. Saxenda may make some oral drugs less effective.
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:
Yellow skin or eyes
Feeling sad or depressed, thoughts of suicide or hurting yourself, unusual changes in mood or behavior
Sudden and severe stomach pain, nausea, vomiting, fever, lightheadedness, yellow skin or eyes
Racing heartbeats
Shaking, trembling, sweating, fast or pounding heartbeat, fainting, hunger, confusion
Change in how much or how often you urinate, painful or burning urination
Trouble breathing or swallowing, a lump in your neck, hoarseness when speaking
Allergic reaction: Itching or hives, skin rash, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Headache
Palpitations
Nausea
Low blood sugar
Vomiting
Diarrhea
Constipation
Headache
Redness, itching, or pain at the injection site
Dizziness
Loss of appetite
Stomach upset
Find more information about Saxenda side effects here.
Saxenda drug summary, Prescriber’s Digital Reference (PDR)
Saxenda liraglutide injection prescribing information, DailyMed (NIH National Library of Medicine)
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