Victoza is a brand-name antidiabetic drug used to reduce and manage blood sugar levels. Its active ingredient, liraglutide, is very similar to the active ingredient in Ozempic and has the same mechanism of action. As a GLP-1 agonist, liraglutide increases insulin, inhibits the body’s natural blood sugar production, slows gastric emptying, and decreases appetite. A significant often desired side effect is weight loss, so the manufacturer also sells liraglutide as brand-name Saxenda, a weight-loss medication.
Victoza
Liraglutide
Treats Type 2 diabetes and reduces the risk of heart attacks and strokes in patients with Type 2 diabetes
Antidiabetic, glucagon-like peptide-1 receptor agonist (GLP-1 receptor agonist)
Injectable
By injection
Victoza helps patients with Type 2 diabetes reduce and control blood sugar and reduce the risk of cardiovascular events if they’re at risk.
Victoza is a brand-name medication used to control diabetes and for weight loss.
It is dosed daily and given under the skin by injection.
Make sure your provider and pharmacist know which other medications and supplements you take to ensure that there are no interactions.
Multiple-dose injection pen
18 mg/3 mL (6 mg/mL)
For Type 2 diabetes:
In adults: 0.6–1.8 subcutaneous injection administered once daily
In children 10 years of age and older: 0.6–1.8 subcutaneous injection administered once daily
Find more information about Victoza dosage, forms, and strengths here.
Victoza
18mg/3ml (6mg/ml) 3ml pen
Follow the instructions given by a healthcare provider when taking this medicine.
Victoza injections are self-administered once a day under the skin.
The Victoza pen is a multi-dose pen. You will use the same pen for several days until the doses run out. The number of doses in the pen will depend on the daily dosage prescribed.
A healthcare provider or pharmacist will demonstrate how to self-administer Victoza injections and where to give injections. Be sure you understand these instructions.
Please read the medication guide that comes with this medicine before taking the first dose.
Please review the prescription Instructions before use.
When first using the pen:
Remove the pen from the refrigerator.
Remove the cap from the pen.
Attach a needle. Use only Novo Nordisk disposable needles on the pen.
Remove the outer and inner caps from the needle.
Follow the Instructions to remove air bubbles from the medicine.
Preparing the injection:
Remove the pen injector from the refrigerator.
Wash your hands.
Check the pen label to confirm the medication is Victoza (liraglutide).
Pull off the pen cap. Discard the pen if the medicine is discolored, cloudy, or contains particles.
Wipe the rubber stop.
Attach the needle. Use only Novo Nordisk disposable needles.
Pull off the outer and inner needle caps.
Dial the proper dose (0.6 mg, 1.2 mg, 1.8 mg) into the pen.
Giving the injection:
You can administer injections in the abdomen, upper arms, or thighs.
Rotate the injection site use a new injection site for each day’s dose.
Insert the needle under the skin.
Press the dose button until the dial has returned to zero AND then for an additional six seconds.
Keep the dose button pressed down and pull straight up to remove the needle.
Put the outer cap back on the needle.
Screw off the needle and put the needle in a sharps container.
Replace the cap on the Victoza pen.
Store Victoza pens in the refrigerator in their original carton to protect it from light and heat. Do not freeze.
Use a new needle for each injection.
If a pen is removed from the refrigerator, it can be stored at room temperature for up to 30 days. Keep the pen away from sunlight and protected from heat.
Dispose of the pen after 30 days, even if there’s still medicine left.
Do not share a pen with another patient, even if the needle is new.
Also, dispose of the pen if it runs out of doses or is exposed to temperatures hotter than 86˚F.
If you miss a dose of this medicine, skip the missed dose and return to your regular dosing schedule.
Never take extra medicine to make up for a missed dose.
If doses are missed for three days or more, contact the prescribing healthcare provider. The doctor will restart treatment at the lowest possible dose.
This medicine is not right for everyone.
Do not use it if you have had a reaction to liraglutide or if you have:
Type 1 diabetes
Multiple endocrine neoplasia syndrome type 2 (MEN 2)
A personal or family history of medullary thyroid cancer (MTC)
The prescribing doctor will see you regularly and administer blood tests to make sure Victoza is working and that you are on the correct dose. They will also confirm that the medication is not causing problems. Keep all appointments.
Tell any doctor or other healthcare provider who treats you that you are using Victoza.
Before starting Victoza, tell the prescriber if you are pregnant, breastfeeding, or have:
Liver problems
Kidney problems
Pancreas problems
Stomach problems, particularly slowed stomach emptying or issues digesting foods
Victoza can cause serious problems, including:
Increased risk of medullary thyroid cancer
Swelling of the pancreas (pancreatitis)
Gallbladder disease
Kidney injury
Low blood sugar
Elevated heart rate
Severe allergic or drug reactions
Victoza can make other oral medications less effective, so tell the prescriber and pharmacist about all prescription drugs, over-the-counter medications, and supplements you take before starting Victoza.
Tell other healthcare professionals about Victoza before they prescribe new medications.
Victoza is more likely to cause low blood sugar in people taking diabetes drugs called insulin secretagogues (meglitinides and sulfonylureas). You can find a complete list of sulfonylureas here and meglitinides here.
Talk to a doctor if you notice any signs or symptoms of a possible serious side effect, including:
Decrease in how much or how often you urinate, lower back or side pain, blood in your urine
Sudden and severe stomach pain, diarrhea, nausea, vomiting, fever
Pale stools, pain in the upper right abdomen, nausea, vomiting, fever, yellowing of the skin or eyes
Shaking, trembling, sweating, fast or pounding heartbeat, lightheadedness, hunger, confusion
Increased neck size, lump in the throat, difficulty swallowing, difficulty breathing
Allergic reaction: Severe rash, severe itching, swelling in your face, lips, tongue, or throat, feeling faint, dizziness, problems breathing, racing heartbeats
Nausea
Vomiting
Diarrhea
Reduced appetite
Headache
Injection site reactions
Find more information about Victoza side effects here.
Liraglutide, StatPearls
Victoza, Novo Nordisk
Victoza drug summary, Prescriber’s Digital Reference (PDR)
Victoza liraglutide injection prescribing information, DailyMed (NIH National Library of Medicine)
Leslie Greenberg, MD, is a board-certified practicing family physician with more than 25 years of doctoring experience. She was a psychology major at Northwestern University near Chicago, then graduated with an MD from the University of Nevada School of Medicine. She completed her family medicine residency at St. Joseph Hospital in Wichita, Kansas. She has trained more than 350 family medicine resident-physicians, been in private practice, and delivered babies for 22 years.
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