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Silvadene overview
BRAND NAMES:
Silvadene, SSD, Thermazene
Generic Names:
Silver Sulfadiazine
Uses:
Prevents and treats skin infections in patients with severe burns.
Therapeutic Classes:
Antibacterial
Forms:
Cream
How it’s taken:
On the skin
What is Silvadene used for?
SSD is a sulfa antibiotic and is used externally to treat bacterial infections caused by severe burns. SSD stops the growth of bacteria that may infect an open burn wound. This prevents bacteria from spreading and causing sepsis. It is indicated for use by adults and is available as a cream.
What form(s) does Silvadene come in
Cream
What are common Silvadene doses?
Tube 20GM of 1%
Tube 25GM of 1%
Tube 50GM of 1%
Tube 85GM of 1%
Jar 50GM of 1%
Jar 400GM of 1%
Jar 1000GM of 1%
Common Silvadene prescriptions
Silvadene
20gm of 1% tubeSilvadene
25gm of 1% tubeSilvadene
50gm of 1% tube of cream
How to take Silvadene
Your doctor will tell you how much medicine to use. Do not use more than directed.
Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.
Topical application routeWash your hands with soap and water before and after you use this medicine.
Before using the cream, clean off any dead skin or scabbing from the burn wound.
Wear sterile gloves to apply this medicine.
Spread a thin layer of the cream over the wound. You may then cover the wound with a bandage if needed.
Keep the wound area clean and covered with the medicine at all times.
If the cream washes off during a bath or other activity, clean the wound again and put on more cream.
To help clear up your skin or burn infection completely, keep using this medicine for the full time of treatment. You should keep using this medicine until the burned area has healed or is ready for skin grafting.
Spread a thin layer of the cream over the wound. You may then cover the wound with a bandage if needed.
To help clear up your skin or burn infection completely, keep using this medicine for the full time of treatment. You should keep using this medicine until the burned area has healed or is ready for skin grafting.
Topical application routeWash your hands with soap and water before and after you use this medicine.
Topical application routeUse this medicine only on your skin. Rinse it off right away if it gets on a cut or scrape. Do not get the medicine in your eyes, nose, or mouth.
Wear sterile gloves to apply this medicine.
If the cream washes off during a bath or other activity, clean the wound again and put on more cream.
Before using the cream, clean off any dead skin or scabbing from the burn wound.
Keep the wound area clean and covered with the medicine at all times.
Your doctor will tell you how much medicine to use. Do not use more than directed.
What to do if you miss a dose of Silvadene
Topical application routeApply a dose as soon as you can. If it is almost time for your next dose, wait until then and apply a regular dose. Do not apply extra medicine to make up for a missed dose.
Topical application routeAsk your pharmacist or doctor how to dispose of the medicine container and any leftover or expired medicine.
Keep all medicine out of the reach of children. Never share your medicine with anyone.
Silvadene contraindications
Do not use this medicine if you have had an allergic reaction to silver sulfadiazine. Do not use this medicine on pregnant women approaching or near giving birth, premature babies, or newborn babies 2 months of age and younger.
Silvadene warnings
Make sure your doctor knows if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, or an enzyme problem called glucose-6-phosphate dehydrogenase (G6PD) deficiency.
This medicine is a sulfa drug (sulfonamide). Rarely, this topical cream might cause some of the side effects seen with oral sulfa drugs. This includes allergic reactions. Check with your doctor right away if you have a blistering, peeling, red skin rash or other severe symptoms (such as unusual bleeding, bruising, or weakness).
If your burn wounds do not heal or if they become worse, call your doctor.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
Silvadene interactions
Make sure your doctor knows if you are also using cimetidine (Tagamet®).
Topical application routeDo not put cosmetics or skin care products on the treated skin.
If your burn wounds do not heal or if they become worse, call your doctor.
Tell any doctor or dentist who treats you that you are using this medicine. This medicine may affect certain medical test results.
Topical application routeDo not use this medicine to treat a skin problem your doctor has not examined.
Silvadene side effects
Serious Side Effects
Unusual bleeding, bruising, weakness
Fever, chills, cough, sore throat, and body aches
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Blistering, peeling, or red skin rash
Change in how much or how often you urinate
Less Serious Side Effects
Skin discomfort when in sunlight
Changes in skin color
Mild rash
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