What is Synera? Uses, warnings & side effects

How to take Synera

• Do not apply this medicine to open wounds, burns, broken, irritated, or inflamed skin, or to a large area of the skin, unless directed by your doctor.

• Do not cut the patch or tear it apart in any way. This could cause medicine to leak out of the patch and burn your skin.

• Do not keep a patch on longer than what your doctor ordered or apply multiple patches at the same time and application site as the first patch.

• Transdermal routeFold the used patch in half with the sticky sides together. Throw any used patch away so that children or pets cannot get to it. You will also need to throw away old patches after the expiration date has passed.

• A nurse or other trained health professional will give you this medicine.

• You may also be taught how to give your medicine at home. Make sure you understand all instructions before you apply the patch. Do not use more medicine or use it more often than your doctor tells you to.

• The patch is applied to your skin about 20 to 30 minutes before your procedure. Do not cover the vent holes in the top of the skin patch while you are wearing it. Tell your doctor if you still have feeling in the skin after 30 minutes have passed.

• This medicine is for use only on the skin. Do not get this medicine into your eyes. If it does get into your eyes, rinse with water or saline solution right away.

• Transdermal routeWash your hands with soap and water before and after applying a patch.

• Transdermal routeLeave the patch in its sealed wrapper until you are ready to put it on. Tear the wrapper open carefully. NEVER CUT the wrapper or the patch with scissors. Do not use any patch that has been cut by accident.

• The patch is applied to your skin about 20 to 30 minutes before your procedure. Do not cover the vent holes in the top of the skin patch while you are wearing it. Tell your doctor if you still have feeling in the skin after 30 minutes have passed.

• Transdermal routeLeave the patch in its sealed wrapper until you are ready to put it on. Tear the wrapper open carefully. NEVER CUT the wrapper or the patch with scissors. Do not use any patch that has been cut by accident.

• You may also be taught how to give your medicine at home. Make sure you understand all instructions before you apply the patch. Do not use more medicine or use it more often than your doctor tells you to.

• Transdermal routeWash your hands with soap and water before and after applying a patch.

• Do not apply this medicine to open wounds, burns, broken, irritated, or inflamed skin, or to a large area of the skin, unless directed by your doctor.

• Do not cut the patch or tear it apart in any way. This could cause medicine to leak out of the patch and burn your skin.

• Do not keep a patch on longer than what your doctor ordered or apply multiple patches at the same time and application site as the first patch.

• This medicine is for use only on the skin. Do not get this medicine into your eyes. If it does get into your eyes, rinse with water or saline solution right away.

• A nurse or other trained health professional will give you this medicine.

• Transdermal routeFold the used patch in half with the sticky sides together. Throw any used patch away so that children or pets cannot get to it. You will also need to throw away old patches after the expiration date has passed.

What to do if you miss a dose of Synera

Synera contraindications - Who shouldn't take Synera?

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to lidocaine, tetracaine, or similar medicines, or para-aminobenzoic acid.

Synera warnings

• Tell your doctor if you are pregnant or breastfeeding, or if you have liver disease, heart problems, lung or breathing problems, a blood disorder, or a genetic disease (including pseudocholinesterase deficiency, G6PD deficiency).

• This medicine may cause methemoglobinemia (blood disorder).

• Your treated skin areas may still be numb for several hours after using the skin patch. Be careful not to accidentally injure the skin by scratching or rubbing it while it is still numb. Avoid exposing the skin to very hot or cold temperatures until your feeling returns.

• Make sure any doctor who treats you knows that you are using this medicine. You must stop using this medicine before you have an MRI (magnetic resonance imaging) scan. You may also need to stop using this medicine before having a breast exam or other medical procedure.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• Shallow or difficulty breathing.

Synera interactions & what to avoid when taking Synera

• Some medicines can affect how lidocaine/tetracaine works. Tell your doctor if you are using any of the following:Acetaminophen, chloroquine, metoclopramide, primaquine, quinine, sulfasalazineCancer medicine (including cyclophosphamide, flutamide, hydroxyurea, ifosfamide, rasburicase)Medicine for heart rhythm problems (including mexiletine, tocainide)Medicine to treat an infection (including dapsone, nitrofurantoin, para-aminosalicylic acid, sulfonamide)Medicine to treat seizures (including phenobarbital, phenytoin, sodium valproate)Nitrate or nitrite medicine (including nitric oxide, nitroglycerin, nitroprusside, nitrous oxide)Other anesthetic medicines

• Tell your doctor if you have had breathing problems caused by general anesthesia during a surgery.

• It is very important to check with your doctor first about using this medicine before having medical tests to examine your breasts or other medical procedures. Using this medicine before having a medical test for your breasts or before having certain other medical procedures may increase your risk of serious side effects.

• You may not have feeling in your treated skin areas for several hours after using the skin patch. Be careful not to accidentally injure the skin by scratching or rubbing it while it is still numb. Avoid exposing the skin to very hot or cold temperatures until your feeling returns.

• If you need to have an MRI (magnetic resonance imaging) scan, the skin patch must be removed before your scan.