What is Tolvaptan: Uses, Warnings & Interactions

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

You need to start or restart this medicine while you are in the hospital. A nurse or other healthcare provider will monitor the sodium levels in your blood. This will allow your doctor to check if this medicine is working well and monitor any unwanted problems that may occur.

This medicine might make you urinate more than usual, so you need to drink water whenever you feel thirsty to stay hydrated.

This medicine is not for long-term use. Most people should not take this medicine for more than 30 days.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Jynarque„¢: If you miss a dose of this medicine, skip the missed dose, and go back to your regular dosing schedule.Samsca®: If you miss a dose of this medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

You need to start or restart this medicine while you are in the hospital. A nurse or other healthcare provider will monitor the sodium levels in your blood. This will allow your doctor to check if this medicine is working well and monitor any unwanted problems that may occur.

This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

Missed dose: Jynarque„¢: If you miss a dose of this medicine, skip the missed dose, and go back to your regular dosing schedule.Samsca®: If you miss a dose of this medicine, use it as soon as you can. If it is almost time for your next dose, wait until then to use the medicine and skip the missed dose. Do not use extra medicine to make up for a missed dose.

This medicine is not for long-term use. Most people should not take this medicine for more than 30 days.

This medicine might make you urinate more than usual, so you need to drink water whenever you feel thirsty to stay hydrated.

Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

Oral routeAsk your pharmacist, doctor, or health caregiver about the best way to dispose of any outdated medicine or medicine no longer needed.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

This medicine is not right for everyone. Do not use it if you had an allergic reaction to tolvaptan, if you are not able to pass urine, or if you cannot tell if you are thirsty.

Tell your doctor if you are pregnant, or if you have kidney disease, liver disease (including cirrhosis), dehydration, or high potassium levels in the blood. Tell your doctor if you have trouble eating enough or might be malnourished. Also tell your doctor if you drink alcohol regularly.

Do not breastfeed during treatment with Jynarque„¢.

This medicine may cause the following problems:Brain or nerve problemsLiver problems

Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

Tell your doctor if you stop taking this medicine. You may need to limit how much water and other beverages you drink. You should never start taking this medicine again on your own. You must do that in a hospital where your sodium levels can be tested.

Keep all medicine out of the reach of children. Never share your medicine with anyone.

Trouble controlling body movement and weakness in the arms or legs

Trouble talking or swallowing

Urinating less or less often than normal

Vomiting, diarrhea

Do not use this medicine if you are also taking clarithromycin, indinavir, itraconazole, ketoconazole, nefazodone, nelfinavir, ritonavir, saquinavir, or telithromycin.

Do not use this medicine together with hypertonic saline, unless your doctor tells you otherwise.

Some medicines can affect how tolvaptan works. Tell your doctor if you are using any of the following:Aprepitant, bosentan, carbamazepine, cyclosporine, desmopressin, digoxin, diltiazem, erythromycin, fluconazole, furosemide, glyburide, methotrexate, nateglinide, phenobarbital, phenytoin, repaglinide, rifabutin, rifampin, rifapentine, rosuvastatin, St John's wortBlood pressure medicine (including benazepril, enalapril, lisinopril, verapamil)Diuretic (water pill)

Ask your doctor first before you use any medicine or salt substitute that contains potassium.

Do not drink alcohol while you are using this medicine.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.