What is Vitrase? Uses, warnings & side effects

Updated May 14, 2025  •  Published Dec 30, 2020

Vitrase overview

BRAND NAMES:

  • Amphadase, Hylenex, Vitrase, Vitrase

Generic Names:

  • Vitrase

Uses:

  • Helps your body absorb other medicines. Also helps add fluid to your body when you are dehydrated.

Therapeutic Classes:

  • Tissue Permeability Modifier

Forms:

  • Injectable

How it’s taken:

  • By injection

What is Vitrase used for?

What form(s) does Vitrase come in?

  • Injectable

What are common Vitrase dosages?

  • Vial 1.2000000476837158ML of 200UNIT/ML

Vitrase images - What does Vitrase look like?

  • Vitrase
    1.2ml of 200unit/ml vial

How to take Vitrase

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Before your injection, you may be given a skin test to make sure you are not allergic to this medicine.

  • Injection routeYour doctor will prescribe your exact dose and tell you how often it should be given. This medicine is given as a shot under your skin.

  • Injection routeA nurse or other health provider will give you this medicine.

  • Before your injection, you may be given a skin test to make sure you are not allergic to this medicine.

What to do if you miss a dose of Vitrase

Vitrase contraindications - Who shouldn't take Vitrase?

  • This medicine is not right for everyone. You should not receive it if you had an allergic reaction to hyaluronidase.

Vitrase warnings

  • Tell your doctor if you are pregnant or breastfeeding.

  • This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns.

Vitrase interactions & what to avoid when taking Vitrase

  • Tell your doctor if you are pregnant or breastfeeding.

  • This medicine is made from donated human blood. All donated blood is tested for certain viruses. Although your risk for getting a virus from the medicine is very low, talk with your doctor if you have concerns.

Vitrase side effects - How does Vitrase make you feel?

Serious Side Effects

  • Rapid weight gain, swelling in your hands, ankles, or feet

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

Less Serious Side Effects

  • Redness, swelling, itching, or pain at the injection site

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