What is Xenleta? Uses, warnings & side effects

How to take Xenleta

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Swallow the tablet whole with water. Do not break, crush, or divide it.

• Take this medicine at least 1 hour before or 2 hours after a meal.

• Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

• Missed dose: If you miss a dose or forget to use your medicine, use it as soon as you can. If your next regular dose is less than 8 hours away, wait until then to use the medicine and skip the missed dose.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Your doctor will tell you how much medicine to use. Do not use more than directed.

• Swallow the tablet whole with water. Do not break, crush, or divide it.

• Take this medicine at least 1 hour before or 2 hours after a meal.

• Take all of the medicine in your prescription to clear up your infection, even if you feel better after the first few doses.

• Missed dose: If you miss a dose or forget to use your medicine, use it as soon as you can. If your next regular dose is less than 8 hours away, wait until then to use the medicine and skip the missed dose.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

• Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be given slowly, so the needle will have to remain in place for at least 1 hour.

• Injection routeA nurse or other health provider will give you this medicine.

• Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein. The medicine must be given slowly, so the needle will have to remain in place for at least 1 hour.

• Injection routeA nurse or other health provider will give you this medicine.

What to do if you miss a dose of Xenleta

Xenleta contraindications - Who shouldn't take Xenleta?

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to lefamulin or similar medicines, or you are pregnant.

• This medicine is not right for everyone. You should not receive it if you had an allergic reaction to lefamulin or similar medicines, or you are pregnant.

Xenleta warnings

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control during treatment and for at least 2 days after the last dose.

• Do not breastfeed during treatment and for at least 2 days after the last dose.

• Tell your doctor if you have kidney disease, liver disease, heart disease, or heart rhythm problem.

• This medicine may cause heart rhythm problem, including QT prolongation.

• This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop using this medicine.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant. Use an effective form of birth control to keep from getting pregnant during treatment and for at least 2 days after the last dose.

• Do not breastfeed during treatment and for at least 2 days after the last dose.

• Tell your doctor if you have kidney disease, liver disease, heart disease, or heart rhythm problem.

• This medicine may cause heart rhythm problem, including QT prolongation.

• This medicine can cause diarrhea. Call your doctor if the diarrhea becomes severe, does not stop, or is bloody. Do not take any medicine to stop diarrhea until you have talked to your doctor. Diarrhea can occur 2 months or more after you stop taking this medicine. It may occur 2 months or more after you stop using this medicine.

• Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

Xenleta interactions & what to avoid when taking Xenleta

• Do not use lefamulin together with any of the following:Erythromycin, moxifloxacinMedicine to treat heart rhythm problems (including amiodarone, quinidine, procainamide, sotalol)Medicine to treat mental illness (including pimozide)Tricyclic antidepressants

• Some medicines may affect how lefamulin works. Tell your doctor if you are using alprazolam, diltiazem, ketoconazole, rifampin, simvastatin, vardenafil, or verapamil.

• Do not use lefamulin together with any of the following:Erythromycin, moxifloxacinMedicine to treat heart rhythm problems (including amiodarone, quinidine, procainamide, sotalol)Medicine to treat mental illness (including pimozide)Tricyclic antidepressants

• Some medicines may affect how lefamulin works. Tell your doctor if you are using alprazolam, diltiazem, ketoconazole, rifampin, simvastatin, vardenafil, or verapamil.