What is Xywav: Uses, Warnings & Interactions

How to take Xywav

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• Measure your dose with the marked plastic syringe that comes with the medicine. Mix it with 1/4 cup of water. Mix both doses before you go to bed. Store the second dose close to your bed, out of the reach of children.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• This medicine is divided into 2 nightly doses. The first nightly dose should be taken at least 2 hours after you eat.

• Take the second dose 2 1/2 to 4 hours after you take the first dose. You may need to set an alarm clock to wake you up so you can take the second dose on time. Remain on your bed after taking the first and second doses of this medicine.

• Missed dose: If you miss the second dose, skip that dose and do not take any more medicine until the next night. Do not use extra medicine to make up for a missed dose.

• Use the medicine within 24 hours after it has been mixed with water.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Pour any unused medicine down the sink drain after 24 hours. Use a marker to cross out the label on the bottle, then throw it in the trash.

• This medicine can make you sleep very quickly (within 5 to 15 minutes) without feeling drowsy. Take it only at bedtime when you are ready to fall asleep. Stay in bed after you take the first dose.

• Use the medicine within 24 hours after it has been mixed with water.

• Take your medicine as directed. Your dose may need to be changed several times to find what works best for you.

• This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

• Measure your dose with the marked plastic syringe that comes with the medicine. Mix it with 1/4 cup of water. Mix both doses before you go to bed. Store the second dose close to your bed, out of the reach of children.

• Missed dose: If you miss the second dose, skip that dose and do not take any more medicine until the next night. Do not use extra medicine to make up for a missed dose.

• Take the second dose 2 1/2 to 4 hours after you take the first dose. You may need to set an alarm clock to wake you up so you can take the second dose on time. Remain on your bed after taking the first and second doses of this medicine.

• This medicine is divided into 2 nightly doses. The first nightly dose should be taken at least 2 hours after you eat.

• Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Pour any unused medicine down the sink drain after 24 hours. Use a marker to cross out the label on the bottle, then throw it in the trash.

• This medicine can make you sleep very quickly (within 5 to 15 minutes) without feeling drowsy. Take it only at bedtime when you are ready to fall asleep. Stay in bed after you take the first dose.

What to do if you miss a dose of Xywav

Xywav contraindications

• This medicine is not right for everyone. Do not use it if you had an allergic reaction to calcium oxybate, magnesium oxybate, potassium oxybate, or sodium oxybate, or if you have succinic semialdehyde dehydrogenase deficiency.

Xywav warnings

• Your doctor will check your progress and the effects of this medicine at regular visits. Keep all appointments.

• Keep all medicine out of the reach of children. Never share your medicine with anyone.

• This medicine may make you dizzy, drowsy, or less alert. Do not drive or do anything else that could be dangerous for at least 6 hours after you take this medicine.

• Tell your doctor if you are pregnant or breastfeeding, or if you have kidney disease, liver disease, lung or breathing problems (including hypopnea, sleep apnea), obesity, or a history of depression or alcohol or drug abuse.

• This medicine can be habit-forming. Do not use more than your prescribed dose. Call your doctor if you think your medicine is not working.

• This medicine may cause the following problems:Serious breathing problems (which can be life-threatening)Changes in mood or behaviorSleeping problems, including sleepwalking, which can cause injuries

Xywav interactions

• Do not drink alcohol while you are using this medicine. Do not use this medicine if you are also using a sedative medicine.

• Some medicines can affect how calcium oxybate/magnesium oxybate/potassium oxybate/sodium oxybate works. Tell your doctor if you are using any of the following:Divalproex sodiumAny other medicine that makes you sleepy, including sleeping pills, cold and allergy medicine, or narcotic pain medicine