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Zoledronic Acid overview
BRAND NAMES:
Reclast, Zoledronic Acid Novaplus, Zoledronic Acid Novaplus, Zometa
Generic Names:
Zoledronic Acid
Uses:
Treats high blood calcium levels. Also treats bone damage caused by Paget disease, multiple myeloma, and cancers that spread to the bone. Also treats osteoporosis and reduces the risk of hip fractures in certain patients.
Therapeutic Classes:
Calcium Regulator
Forms:
Injectable
How it’s taken:
By injection
What is Zoledronic Acid used for?
Reclast is a prescription-only medication that is used to prevent or treat osteoporosis or Paget's disease. Reclast works by increasing bone density within the body in order to create and maintain strong, healthy bones.
What form(s) does Zoledronic Acid come in
Injectable
What are common Zoledronic Acid doses?
Bottle 100ML of 5MG/100ML
Vial 5ML of 4MG/5ML
Vial 100ML of 4MG/100ML
Vial 100ML of 5MG/100ML
Flex Cont 100ML of 4MG/100ML
Flex Cont 100ML of 5MG/100ML
Plas Cont 100ML of 4MG/100ML
Bag 100ML of 5MG/100ML
Common Zoledronic Acid prescriptions
Zoledronic Acid
100ml of 5mg/100ml bagZoledronic Acid
100ml of 4mg/100ml bottleZoledronic Acid
100ml of 5mg/100ml bottleZoledronic Acid
100ml of 4mg/100ml flex contZoledronic Acid
100ml of 5mg/100ml flex contZoledronic Acid
4mg solution reconstitutedZoledronic Acid
100ml of 4mg/100ml vialZoledronic Acid
100ml of 5mg/100ml vialZoledronic Acid
5ml of 4mg/5ml vial
How to take Zoledronic Acid
Injection routeA nurse or other health provider will give you this medicine.
Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
Your doctor may tell you to drink extra liquids before your treatment to prevent kidney problems.
Your doctor may also give you vitamin D and calcium supplements. Tell your doctor if you are not able to take these medicines.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Missed dose:You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.
Your doctor may tell you to drink extra liquids before your treatment to prevent kidney problems.
Your doctor may also give you vitamin D and calcium supplements. Tell your doctor if you are not able to take these medicines.
Injection routeA nurse or other health provider will give you this medicine.
Injection routeYour doctor will prescribe your dose and schedule. This medicine is given through a needle placed in a vein.
This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.
Missed dose:You must use this medicine on a fixed schedule. Call your doctor or pharmacist if you miss a dose.
What to do if you miss a dose of Zoledronic Acid
Zoledronic Acid contraindications
This medicine is not right for everyone. You should not receive it if you had an allergic reaction to zoledronic acid, or if you are pregnant.
Zoledronic Acid warnings
It is not safe to take this medicine during pregnancy. It could harm an unborn baby. Tell your doctor right away if you become pregnant.
Tell your doctor if you are breastfeeding, or if you have kidney disease, anemia, aspirin-sensitive asthma, bleeding problems, cancer, congestive heart failure, low blood calcium levels, stomach absorption problems, mineral imbalance, dental problems or gum disease. Also tell your doctor if you had surgery on your bowel or parathyroid or thyroid gland.
This medicine may cause the following problems:Jaw or teeth problemsSevere bone, joint, or muscle painIncreased risk of thigh bone fractureLow calcium levels in your blood
You must have regular dental exams while you are being treated with this medicine. Tell your dentist or oral surgeon that you are using this medicine.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Severe muscle, bone, or joint pain
Unusual pain in your thigh, groin, or hip
Zoledronic Acid interactions
Do not use other medicines that also contain zoledronic acid. Do not use zoledronic acid together with another bisphosphonate medicine.
Some foods and medicines can affect how zoledronic acid works. Tell your doctor if you are using digoxin, antibiotics, diuretics (water pills), an NSAID pain or arthritis medicine (such as aspirin, celecoxib, ibuprofen, naproxen), steroid medicines, or cancer medicines.
This medicine may cause the following problems:Jaw or teeth problemsSevere bone, joint, or muscle painIncreased risk of thigh bone fractureLow calcium levels in your blood
You must have regular dental exams while you are being treated with this medicine. Tell your dentist or oral surgeon that you are using this medicine.
Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.
Zoledronic Acid side effects
Serious Side Effects
Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing
Chest pain, trouble breathing, fast or uneven heartbeat
Decrease in how much or how often you urinate, blood in the urine, lower back or side pain, burning or painful urination
Muscle spasm or twitching, or numbness or tingling in your fingers, feet, or around your mouth
Severe muscle, bone, or joint pain
Unusual pain in your thigh, groin, or hip
Pain, swelling, or numbness in the mouth or jaw, loose teeth or other teeth problems
Less Serious Side Effects
Fever, chills, cough, sore throat, and body aches
Redness, pain, or swelling of your skin where the needle is placed
Headache
Mild nausea, constipation, diarrhea, stomach pain or upset
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