Every July, drug manufacturers make their biannual adjustments to drug prices and this past month was no exception, as inflation as measured by the Consumer Price Index (CPI) exceeded 9% in June, the highest rate in decades. In July 2022, 64 drug manufacturers increased the average wholesale prices (AWP) of prescription drugs for the second half of the year as 120 individual brand prescription medications rose in price by an average of 8.7%.
“We know drug manufacturers update their prices every July so it’s to be expected that this year was no different, especially in light of historic inflation,” said Ramzi Yacoub, Pharm D., the chief pharmacy officer for SingleCare. “The silver lining for most consumers is that it is unlikely these changes will impact the cost of their prescription at the pharmacy. The majority of these drugs are brand or specialty medications and consumers most commonly fill generics– about 90% of the time – and these drugs are typically far less expensive and with prices that remain relatively flat year over year.”
SingleCare reviewed the drugs that will see the highest dollar increase in July 2022 compared to the previous year based on the average wholesale price (AWP), set by manufacturers. While consumers never pay AWP at the pharmacy – they will either pay a funded rate through their insurance, or retail cost with the opportunity to get discounted rates through prescription savings services like SingleCare, or manufacturer discounts (copay cards or patient assistance programs) for brand drugs – this represents a baseline cost with potential trickle down cost increases to the consumer as well.
Note, while these drugs have the largest AWP increase, these are generally specialty drugs that are not commonly prescribed and typically see lower consumer utilization.

According to a June SingleCare survey, 42% of respondents said rising inflation rates have made it more difficult for them to afford their prescription this year. Additionally, the survey also revealed that nearly half (48%) find it more difficult to afford their prescriptions this year compared to last. With historic inflation rates and the rising costs of goods, it’s now more important than ever that consumers know of cost saving alternatives when it comes to their prescription drugs.
Access and adherence to prescription medications is vital, especially for those who have a chronic condition. SingleCare provides consumers up to 80% off their medications on over 10,000 drugs at 35,000 pharmacies nationwide. It’s always worth checking SingleCare as it’s almost always less expensive than the cash price of the drug if you're paying out of pocket, and it's often cheaper than a co-pay.
SingleCare’s drug pricing analysis tracks the individual brand drugs that saw an average wholesale price (AWP) change from July 2022 compared to July 2021. This excludes over-the-counter medications and medical devices. SingleCare has updated and reviewed this data as of July 18, 2022.
SingleCare conducted the prescription affordability survey online through SurveyMonkey on June 29, 2022. This survey includes 1,083 United States residents, adults ages 18+. Age and gender were census-balanced to match the U.S. population in age, gender, and U.S. region.
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SingleCare is a prescription discount service that offers free coupons on thousands of prescription drugs. It can be used whether you have insurance, Medicare, Medicaid, or none of the above, but it cannot be combined with insurance.
SingleCare provides transparent drug pricing, so you can compare discounts at pharmacies near you. Browse singlecare.com to find drug discounts, helpful information about your prescription, and resources to help you make informed health decisions.
Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved