The drug prices in 2021 have already seen dramatic price changes: 1,283 individual prescription drugs have increased in price in the first seven months of the year, which represents a 16% jump compared to the same time period last year.
While prices are typically announced in January and July, the stark reality is that drug manufacturers are continually adjusting the price of prescription drugs throughout the entire year. Even though January is historically the month that sees the greatest amount of drug price increases (937 in January 2021), SingleCare has seen an additional 464 individual prescription drug prices increase from February to July 2021, which is up 28% compared to the same time period last year.
Looking ahead, drug manufacturers have already begun to increase the average wholesale prices (AWP) of prescription drugs for July: 110 individual prescription drugs saw a price increase in July, at an average of 65% or $70.79.

“In the first half of 2021, we’ve already seen a marked increase in the number of drugs on which manufacturers have raised prices,” said Ramzi Yacoub, Pharm. D., the chief pharmacy officer for SingleCare. “These changes can trickle down and impact the price of drugs that consumers pay at the pharmacy. As the majority of adjustments are typically made to brand medications, the good news for consumers filling generic drugs, which account for 90% of all fills, is these prices are less likely to change.”
“As prescription drug prices change regularly, and the same drug can differ in price from manufacturer to manufacturer, it pays to check SingleCare prescription coupons to ensure you’re getting the lowest cost option,” Dr. Yacoub continued. “While most consumers filling generics likely won’t feel a significant impact to their wallet, it’s a reminder to those filling more expensive brand medications to continue to seek out generic options whenever possible.”
The average American fills nearly three scripts per month and spends $1,200 each year on their medications—which is more than any other country in the world. SingleCare reviewed the drugs that will see the highest dollar increase in July 2021 compared to the previous year based on the average wholesale price (AWP), which is set by the manufacturer. While these drugs see the highest dollar increase, they are not commonly prescribed drugs and typically see lower utilization.
SingleCare’s drug pricing analysis tracks the individual drugs that saw an average wholesale price (AWP) change from 2021 compared to 2020 based on MediSpan data. This excludes over-the-counter medications. SingleCare has updated and reviewed this data as of Jul. 12, 2021.
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Prescription savings vary by prescription and by pharmacy, and may reach up to 80% off cash price. This is a medical discount plan. This is NOT insurance. This program offers you the opportunity to locate providers of various types of medical services who will offer their services to you at discounted rates. The range of discounts for medical or ancillary services provided under the plan will vary depending on the type of provider and service received. You are fully responsible for paying for all health care services but will be entitled to receive a discount from those health care providers in accordance with the specific pre-negotiated discounted fee schedule. This program does not guarantee the quality of the services or procedures offered by the providers. Except for prescription drugs which you will pay directly to the pharmacy at the time of purchase, all other services received through a program provider will be charged to the credit card on file in your member account. The charge will include an administrative fee for use of the program. Towers Administrators LLC is the licensed discount medical plan organization with its administrative office located at 4510 Cox Road, Suite 111, Glen Allen, VA 23060. SingleCare Services, LLC is the marketer of the discount medical plan organization including its website, singlecare.com, with its corporate office located at 99 High Street, Suite 2800, Boston, MA 02110. For additional information, including an up-to-date list of providers, or assistance with any issue related to program membership, please contact member support any time at www.singlecare.com, or by calling toll-free 844-234-3057, 24 hours, 7 days a week (except major holidays). Pharmacy names, logos, brands, and other trademarks are the property of their respective owners.
Blog articles are not medical advice. They are intended for general informational purposes and are not meant to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. If you think you may have a medical emergency, immediately call your physician or dial 911.
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© 2025 SingleCare Administrators. All rights reserved