Can you take Tylenol with gabapentin?

Medically reviewed by Jessica SwirblePharm.D.
Licensed Pharmacist
Updated Jan 9, 2026  •  Published Jan 9, 2026
Fact Checked

Yes, you can take Tylenol with gabapentin safely. They don’t interact or reduce each other’s effectiveness because they work through different mechanisms; gabapentin targets nerve pain, while Tylenol relieves general aches. This combination can provide broader pain relief; however, gabapentin may cause dizziness or fatigue, and Tylenol should be taken within the recommended doses.

Want to learn more Tylenol and gabapentin?  Read our full article: Do gabapentin and Tylenol mix?


Medical disclaimer: This content is for general informational purposes only and does not constitute medical advice. Always consult your healthcare provider before making changes to your medication regimen.

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Medically reviewed by Jessica SwirblePharm.D.
Licensed Pharmacist

Jessica Swirble, Pharm.D., is a 2007 graduate of the Philadelphia College of Pharmacy and has more than 16 years of experience as a pharmacist. She currently resides in Pennsylvania and works as a community pharmacist. She is also a freelance medical writer and reviewer. When away from work, she enjoys traveling, baking, reading, and spending time with her family.

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