What is Abacavir: Uses, Warnings & Interactions

Updated May 6, 2025  •  Published Dec 30, 2020

Abacavir overview

BRAND NAMES:

  • Ziagen

Generic Names:

  • Abacavir Sulfate

Uses:

  • Treats HIV infection. HIV causes AIDS. This medicine does not cure HIV or AIDS, but combinations of drugs may slow the progress of the disease.

Therapeutic Classes:

  • Antiretroviral Agent

Forms:

  • Liquid, Tablet

How it’s taken:

  • By mouth

What is Abacavir used for?

Ziagen is a prescription-only medication that is used to treat patients diagnosed with human immunodeficiency virus (HIV). Ziagen works by decreasing the growth of HIV cells within the body to help the patient’s immune system from receiving HIV related complications including tuberculosis and lymphoma.

What form(s) does Abacavir come in

  • Liquid

  • Tablet

What are common Abacavir doses?

  • Tablet 300MG

  • Bottle 240ML of 20MG/ML

Common Abacavir prescriptions

  • Abacavir Sulfate
    240ml of 20mg/ml bottle

  • Abacavir Sulfate
    300mg tablet

How to take Abacavir

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Do not stop using this medicine without checking first with your doctor. If you stop the medicine even for a short time, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. You may store the oral liquid in the refrigerator, but do not freeze it.

  • Your doctor will tell you how much medicine to use. Do not use more than directed.

  • This medicine should come with a Medication Guide. Ask your pharmacist for a copy if you do not have one.

  • Oral liquid: Measure the oral liquid medicine with a marked measuring spoon, oral syringe, or medicine cup.

  • Missed dose: Take a dose as soon as you remember. If it is almost time for your next dose, wait until then and take a regular dose. Do not take extra medicine to make up for a missed dose.

  • Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. You may store the oral liquid in the refrigerator, but do not freeze it.

  • Do not stop using this medicine without checking first with your doctor. If you stop the medicine even for a short time, the virus may become harder to treat. Contact your doctor or pharmacist when your supply is running low so you do not run out.

What to do if you miss a dose of Abacavir

Abacavir contraindications

  • This medicine is not right for everyone. Do not use it if you had an allergic reaction to abacavir.

Abacavir warnings

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Tell your doctor if you are pregnant, or if you have liver disease, diabetes, heart disease, high blood pressure, or high cholesterol. Tell your doctor if you smoke or drink alcohol.

  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.

  • This medicine may cause the following problems:Serious allergic reactions that may involve multiple organs, such as your liver or kidneysLactic acidosisSevere liver problemsIncreased risk of heart attack

  • Your immune system may get stronger when you start taking HIV medicines. This could cause a hidden infection in your body to become active. Tell your doctor right away if you notice any changes in your health.

  • Do not stop using this medicine without checking with your doctor first. If you stop the medicine even briefly, the virus may become harder to treat.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

Abacavir interactions

  • Some medicines can affect how abacavir works. Tell your doctor if you are using methadone.

  • Do not breastfeed. You can spread HIV or AIDS to your baby through your breast milk.

  • This medicine may cause the following problems:Serious allergic reactionLactic acidosisLiver problemsIncreased risk of heart attack

  • Your immune system may get stronger when you start taking HIV medicines. Sometimes the immune system will start to fight infections that were hidden in your body, such as pneumonia or tuberculosis. Tell your doctor right away if you notice any changes in your health.

  • Do not stop using this medicine without checking with your doctor first. If you stop the medicine even briefly, the virus may become harder to treat.

  • This medicine will not keep you from giving HIV to others. Always practice safe sex, even if your partner also has HIV. Do not share needles or other items that may have blood or body fluids on them.

  • Your doctor will do lab tests at regular visits to check on the effects of this medicine. Keep all appointments.

  • Keep all medicine out of the reach of children. Never share your medicine with anyone.

Abacavir side effects

Serious Side Effects

  • Fever, rash, cough, sore throat, nausea, vomiting, diarrhea, joint or muscle aches, unusual tiredness or weakness

  • Dark urine or pale stools, loss of appetite, stomach pain, yellow skin or eyes

  • Fast breathing, lightheadedness, dizziness, severe weakness, confusion

  • Allergic reaction: Itching or hives, swelling in your face or hands, swelling or tingling in your mouth or throat, chest tightness, trouble breathing

  • Blistering, peeling, red skin rash

  • Chest pain that may spread, trouble breathing, unusual sweating, faintness

Less Serious Side Effects

  • Headache

  • Mild nausea, vomiting, or diarrhea

  • Weight gain around your neck, upper back, breast, or waist